Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:BCAP_HUMAN
Description:phosphoinositide-3-kinase adaptor protein 1 [Source:HGNC Symbol;Acc:30034]
Location:chr10 q24.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S562VFAEKsQERPGPhosphoSitePlus
T658LRDSItRRQREPhosphoSitePlus
Y133DEPETyVAAVKPhosphoSitePlus
Y513QEEDVyHTVDDPhosphoSitePlus
Y694VEFGVyESGPRPhosphoSitePlus; HPRD; SysPTM
Y163EKVVSySKQQNPhosphoSitePlus
S145AISEDsGCDSVPhosphoSitePlus
S642KKRSEsFRFQQPhosphoSitePlus; HPRD
S718DWKTDsTSSTAPhosphoSitePlus
Y230KVENEyTISVKPhosphoSitePlus
Y553PDNEPyIFKVFPhosphoSitePlus
S575YVSSEsIRKGPPhosphoSitePlus
S656KRLRDsITRRQPhosphoSitePlus; HPRD
Y594PQSSIyDPFAGPhosphoSitePlus
T151GCDSVtDTEPEPhosphoSitePlus
Y570RPGNFyVSSESPhosphoSitePlus; HPRD
Y419EADAVyESMAHPhosphoSitePlus

Dephosphorylation site
BCAP_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000339826G495RCOSMICSkin Cancer21984974
ENSP00000339826A136DCOSMICHead and Neck Cancer21798893
ENSP00000360151T219MBIOMARTBreast Cancer21930507, 21930502
ENSP00000339826T722KCOSMICSkin Cancer21984974
ENSP00000339826T352SCOSMICHead and Neck Cancer21798897
ENSP00000339826T397MBIOMARTBreast Cancer21930507, 21930502
ENSP00000339826G313RCOSMICHead and Neck Cancer21798897
ENSP00000339826R478QCOSMICHead and Neck Cancer21798897
ENSP00000339826G618SCOSMICOvarian Cancer21720365

Differential expressed protein
BCAP_HUMAN is not differential expressed protein.

Hyperphosphorylation site
BCAP_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KSYK_HUMANBCAP_HUMANkinase -> substrateKEGG; NetPath
BTK_HUMANBCAP_HUMANkinase -> substrateNetPath

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04662B cell receptor signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005737cytoplasmIEAcellular_component
GO:0005829cytosolTAScellular_component
GO:0005886plasma membraneIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0042802identical protein bindingIEAmolecular_function
GO:0005886plasma membraneTAScellular_component


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