| UniProt/SwissProt ID: | ARY1_HUMAN |
| Description: | N-acetyltransferase 1 (arylamine N-acetyltransferase) [Source:HGNC Symbol;Acc:7645] |
| Location: | chr8 p22 |
| Node attribute: | gene |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T25 | DLETLtDILQH | HPRD | |
| Y101 | TPAKKySTGMI | Acetyltransf_2 | PhosphoSitePlus |
| Y208 | ESMNTyLQTSP | Acetyltransf_2 | PhosphoSitePlus |
| Dephosphorylation site |
| ARY1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000429341 | L152F | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000428270 | L152F | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000307218 | L152F | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000429407 | L152F | BIOMART | Breast Cancer | 21930507, 21930502 |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000307218 | Breast Cancer | Normal vs. Cancer | tissue | Up | 0.44 | 20739354 |
| Hyperphosphorylation site |
| ARY1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| JUN_HUMAN | ARY1_HUMAN | TF -> target gene | TRANSFAC |
| FOS_HUMAN | ARY1_HUMAN | TF -> target gene | TRANSFAC |
| TYY1_HUMAN | ARY1_HUMAN | TF -> target gene | TRANSFAC |
| PO2F1_HUMAN | ARY1_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| ARY1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0006805 | xenobiotic metabolic process | TAS | biological_process |
| GO:0016407 | acetyltransferase activity | IEA | molecular_function |
| GO:0044281 | small molecule metabolic process | TAS | biological_process |
| GO:0004060 | arylamine N-acetyltransferase activity | IEA | molecular_function |
| GO:0008152 | metabolic process | IEA | biological_process |