| UniProt/SwissProt ID: | ZN238_HUMAN |
| Description: | zinc finger and BTB domain containing 18 [Source:HGNC Symbol;Acc:13030] |
| Location: | chr1 q44 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S136 | EEDASsCSDKV | PhosphoSitePlus | |
| S526 | TLEDSsQEL | HPRD | |
| S279 | VEKEAsCDESD | PhosphoSitePlus | |
| S516 | WTLEDsSQELW | PhosphoSitePlus | |
| S283 | ASCDEsDVGTN | PhosphoSitePlus | |
| S517 | TLEDSsQEL | HPRD; phosphoELM | |
| S333 | REDKAsDDEMM | PhosphoSitePlus | |
| S189 | WMRLPsDSAGI | PhosphoSitePlus | |
| T507 | ALSLPtVRDWT | PhosphoSitePlus | |
| S525 | WTLEDsSQEL | HPRD | |
| S517 | TLEDSsQELWK | PhosphoSitePlus | |
| S516 | WTLEDsSQEL | HPRD; phosphoELM | |
| Dephosphorylation site |
| ZN238_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000351539 | H73Y | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000351539 | V273M | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000351539 | S390C | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000351539 | *532R | COSMIC | Breast Cancer | 20668451 | ENSP00000351539 | S399C | TCGA | Ovarian Cancer | 21720365, 18772890 |
| Differential expressed protein |
| ZN238_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| ZN238_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CDKL5_HUMAN | ZN238_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| ZN238_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0007519 | skeletal muscle tissue development | IEA | biological_process |
| GO:0021549 | cerebellum development | IEA | biological_process |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0045892 | negative regulation of transcription, DNA-dependen | ISS | biological_process |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0021766 | hippocampus development | IEA | biological_process |
| GO:0048666 | neuron development | IEA | biological_process |
| GO:0048872 | homeostasis of number of cells | IEA | biological_process |
| GO:0043565 | sequence-specific DNA binding | IDA | molecular_function |
| GO:0000122 | negative regulation of transcription from RNA poly | IEA | biological_process |
| GO:0003700 | sequence-specific DNA binding transcription factor | TAS | molecular_function |
| GO:0003677 | DNA binding | TAS | molecular_function |
| GO:0021987 | cerebral cortex development | IEA | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0008270 | zinc ion binding | IEA | molecular_function |
| GO:0051302 | regulation of cell division | IEA | biological_process |
| GO:0045892 | negative regulation of transcription, DNA-dependen | IEA | biological_process |
| GO:0000228 | nuclear chromosome | TAS | cellular_component |
| GO:0005634 | nucleus | TAS | cellular_component |
| GO:0001701 | in utero embryonic development | IEA | biological_process |
| GO:0000122 | negative regulation of transcription from RNA poly | ISS | biological_process |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0007519 | skeletal muscle tissue development | ISS | biological_process |