Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ZN238_HUMAN
Description:zinc finger and BTB domain containing 18 [Source:HGNC Symbol;Acc:13030]
Location:chr1 q44
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S136EEDASsCSDKVPhosphoSitePlus
S526TLEDSsQELHPRD
S279VEKEAsCDESDPhosphoSitePlus
S516WTLEDsSQELWPhosphoSitePlus
S283ASCDEsDVGTNPhosphoSitePlus
S517TLEDSsQELHPRD; phosphoELM
S333REDKAsDDEMMPhosphoSitePlus
S189WMRLPsDSAGIPhosphoSitePlus
T507ALSLPtVRDWTPhosphoSitePlus
S525WTLEDsSQELHPRD
S517TLEDSsQELWKPhosphoSitePlus
S516WTLEDsSQELHPRD; phosphoELM

Dephosphorylation site
ZN238_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000351539H73YBIOMARTBreast Cancer21930507, 21930502
ENSP00000351539V273MTCGAOvarian Cancer21720365, 18772890
ENSP00000351539S390CTCGAOvarian Cancer21720365, 18772890
ENSP00000351539*532RCOSMICBreast Cancer20668451
ENSP00000351539S399CTCGAOvarian Cancer21720365, 18772890

Differential expressed protein
ZN238_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ZN238_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CDKL5_HUMANZN238_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
ZN238_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0007519skeletal muscle tissue developmentIEAbiological_process
GO:0021549cerebellum developmentIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0045892negative regulation of transcription, DNA-dependenISSbiological_process
GO:0005622intracellularIEAcellular_component
GO:0021766hippocampus developmentIEAbiological_process
GO:0048666neuron developmentIEAbiological_process
GO:0048872homeostasis of number of cellsIEAbiological_process
GO:0043565sequence-specific DNA bindingIDAmolecular_function
GO:0000122negative regulation of transcription from RNA polyIEAbiological_process
GO:0003700sequence-specific DNA binding transcription factorTASmolecular_function
GO:0003677DNA bindingTASmolecular_function
GO:0021987cerebral cortex developmentIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0008270zinc ion bindingIEAmolecular_function
GO:0051302regulation of cell divisionIEAbiological_process
GO:0045892negative regulation of transcription, DNA-dependenIEAbiological_process
GO:0000228nuclear chromosomeTAScellular_component
GO:0005634nucleusTAScellular_component
GO:0001701in utero embryonic developmentIEAbiological_process
GO:0000122negative regulation of transcription from RNA polyISSbiological_process
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0007519skeletal muscle tissue developmentISSbiological_process


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