| UniProt/SwissProt ID: | ZN148_HUMAN |
| Description: | zinc finger protein 148 [Source:HGNC Symbol;Acc:12933] |
| Location: | chr3 q21.2 |
| Node attribute: | TF |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T670 | SPLRTtPDKSH | PhosphoSitePlus; HPRD | |
| S400 | INSKRsLKQPL | PhosphoSitePlus | |
| S784 | AGMTSsPDATT | PhosphoSitePlus; HPRD; phosphoELM | |
| Y417 | SPLSTyEESKV | PhosphoSitePlus | |
| S423 | EESKVsKYAFE | PhosphoSitePlus | |
| T782 | NRAGMtSSPDA | HPRD | |
| Y259 | PYQCEyCLQYF | zf-C2H2 | PhosphoSitePlus |
| Y425 | SKVSKyAFELV | PhosphoSitePlus | |
| S311 | SPKDNsLPKKK | HPRD; phosphoELM | |
| S306 | SGFSTsPKDNS | PhosphoSitePlus; HPRD; phosphoELM | |
| T305 | DSGFStSPKDN | PhosphoSitePlus; HPRD; phosphoELM | |
| T25 | MQSSRtMVVMG | PhosphoSitePlus; HPRD; phosphoELM | |
| S661 | INSFRsGMNSP | PhosphoSitePlus | |
| S325 | TEKKSsGMDKE | PhosphoSitePlus | |
| Y349 | DYLPLySSSTK | PhosphoSitePlus | |
| S415 | TISPLsTYEES | PhosphoSitePlus | |
| S665 | RSGMNsPLRTT | PhosphoSitePlus; HPRD | |
| S250 | HKRTHsGEKPY | PhosphoSitePlus; HPRD; phosphoELM | |
| T788 | SSPDAtTGQT | HPRD | |
| S627 | YLNSPsLNFVT | PhosphoSitePlus | |
| S202 | KPFQCsQCDMR | zf-C2H2 | PhosphoSitePlus |
| S301 | TSEEDsGFSTS | PhosphoSitePlus | |
| S412 | QNQTIsPLSTY | PhosphoSitePlus; HPRD; phosphoELM | |
| S740 | APYHGsRAGIA | PhosphoSitePlus | |
| T669 | NSPLRtTPDKS | HPRD | |
| S304 | EDSGFsTSPKD | HPRD | |
| T194 | HVFIHtGEKPF | PhosphoSitePlus; HPRD; phosphoELM | |
| T37 | VSGQStVSGEL | HPRD; phosphoELM | |
| S331 | GMDKEsALDKS | PhosphoSitePlus | |
| Dephosphorylation site |
| ZN148_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000353863 | D510Y | COSMIC | Pancreatic Cancer | |
| ENSP00000419322 | T565S | BIOMART | Breast Cancer | 21930507, 21930502 |
| ENSP00000420448 | T565S | BIOMART | Breast Cancer | 21930507, 21930502 |
| ENSP00000353863 | D465V | COSMIC | Ovarian Cancer | 21720365 |
| ENSP00000353863 | T565S | BIOMART | Breast Cancer | 21930507, 21930502 |
| ENSP00000353863 | P770S | COSMIC | Melanoma | 21499247 |
| ENSP00000353863 | S674F | COSMIC | Melanoma | 21499247 |
| ENSP00000420448 | D510Y | BIOMART | Pancreatic Cancer | 21930507, 21930502 |
| Differential expressed protein |
| ZN148_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| ZN148_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ZN148_HUMAN | MMP3_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| ZN148_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0003700 | sequence-specific DNA binding transcription factor | IEA | molecular_function |
| GO:0000976 | transcription regulatory region sequence-specific | IEA | molecular_function |
| GO:0000122 | negative regulation of transcription from RNA poly | IEA | biological_process |
| GO:0043565 | sequence-specific DNA binding | IDA | molecular_function |
| GO:0008270 | zinc ion binding | IEA | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0006461 | protein complex assembly | IEA | biological_process |
| GO:0007276 | gamete generation | IEA | biological_process |
| GO:0045944 | positive regulation of transcription from RNA poly | IEA | biological_process |
| GO:0006968 | cellular defense response | TAS | biological_process |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0003690 | double-stranded DNA binding | IEA | molecular_function |
| GO:0006366 | transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0045892 | negative regulation of transcription, DNA-dependen | IDA | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0010629 | negative regulation of gene expression | IDA | biological_process |