UniProt/SwissProt ID: | ZN148_HUMAN |
Description: | zinc finger protein 148 [Source:HGNC Symbol;Acc:12933] |
Location: | chr3 q21.2 |
Node attribute: | TF |
Phosphorylation site |
Position | PhosphoPeptide | Catalytic kinase | Source |
---|---|---|---|
T670 | SPLRTtPDKSH | PhosphoSitePlus; HPRD | |
S400 | INSKRsLKQPL | PhosphoSitePlus | |
S784 | AGMTSsPDATT | PhosphoSitePlus; HPRD; phosphoELM | |
Y417 | SPLSTyEESKV | PhosphoSitePlus | |
S423 | EESKVsKYAFE | PhosphoSitePlus | |
T782 | NRAGMtSSPDA | HPRD | |
Y259 | PYQCEyCLQYF | zf-C2H2 | PhosphoSitePlus |
Y425 | SKVSKyAFELV | PhosphoSitePlus | |
S311 | SPKDNsLPKKK | HPRD; phosphoELM | |
S306 | SGFSTsPKDNS | PhosphoSitePlus; HPRD; phosphoELM | |
T305 | DSGFStSPKDN | PhosphoSitePlus; HPRD; phosphoELM | |
T25 | MQSSRtMVVMG | PhosphoSitePlus; HPRD; phosphoELM | |
S661 | INSFRsGMNSP | PhosphoSitePlus | |
S325 | TEKKSsGMDKE | PhosphoSitePlus | |
Y349 | DYLPLySSSTK | PhosphoSitePlus | |
S415 | TISPLsTYEES | PhosphoSitePlus | |
S665 | RSGMNsPLRTT | PhosphoSitePlus; HPRD | |
S250 | HKRTHsGEKPY | PhosphoSitePlus; HPRD; phosphoELM | |
T788 | SSPDAtTGQT | HPRD | |
S627 | YLNSPsLNFVT | PhosphoSitePlus | |
S202 | KPFQCsQCDMR | zf-C2H2 | PhosphoSitePlus |
S301 | TSEEDsGFSTS | PhosphoSitePlus | |
S412 | QNQTIsPLSTY | PhosphoSitePlus; HPRD; phosphoELM | |
S740 | APYHGsRAGIA | PhosphoSitePlus | |
T669 | NSPLRtTPDKS | HPRD | |
S304 | EDSGFsTSPKD | HPRD | |
T194 | HVFIHtGEKPF | PhosphoSitePlus; HPRD; phosphoELM | |
T37 | VSGQStVSGEL | HPRD; phosphoELM | |
S331 | GMDKEsALDKS | PhosphoSitePlus | |
Dephosphorylation site |
ZN148_HUMAN do not have dephosphorylation site. |
Mutation site |
Ensembl ID | Variation | Source | Cancer name | Pubmed |
---|---|---|---|---|
ENSP00000353863 | D510Y | COSMIC | Pancreatic Cancer | |
ENSP00000419322 | T565S | BIOMART | Breast Cancer | 21930507, 21930502 |
ENSP00000420448 | T565S | BIOMART | Breast Cancer | 21930507, 21930502 |
ENSP00000353863 | D465V | COSMIC | Ovarian Cancer | 21720365 |
ENSP00000353863 | T565S | BIOMART | Breast Cancer | 21930507, 21930502 |
ENSP00000353863 | P770S | COSMIC | Melanoma | 21499247 |
ENSP00000353863 | S674F | COSMIC | Melanoma | 21499247 |
ENSP00000420448 | D510Y | BIOMART | Pancreatic Cancer | 21930507, 21930502 |
Differential expressed protein |
ZN148_HUMAN is not differential expressed protein. |
Hyperphosphorylation site |
ZN148_HUMAN do not have hyperphosphorylation site. |
Direct Interaction Pair |
Source | Target | Relationship | Resource |
---|---|---|---|
ZN148_HUMAN | MMP3_HUMAN | TF -> target gene | TRANSFAC |
Function Annotation |
KEGG Pathway |
ZN148_HUMAN is not in KEGG pathway. |
Gene Ontology |
GO ID | GO_Term | Evidence | Ontology |
---|---|---|---|
GO:0005794 | Golgi apparatus | IDA | cellular_component |
GO:0003700 | sequence-specific DNA binding transcription factor | IEA | molecular_function |
GO:0000976 | transcription regulatory region sequence-specific | IEA | molecular_function |
GO:0000122 | negative regulation of transcription from RNA poly | IEA | biological_process |
GO:0043565 | sequence-specific DNA binding | IDA | molecular_function |
GO:0008270 | zinc ion binding | IEA | molecular_function |
GO:0003677 | DNA binding | IEA | molecular_function |
GO:0006461 | protein complex assembly | IEA | biological_process |
GO:0007276 | gamete generation | IEA | biological_process |
GO:0045944 | positive regulation of transcription from RNA poly | IEA | biological_process |
GO:0006968 | cellular defense response | TAS | biological_process |
GO:0005634 | nucleus | IEA | cellular_component |
GO:0005622 | intracellular | IEA | cellular_component |
GO:0003690 | double-stranded DNA binding | IEA | molecular_function |
GO:0006366 | transcription from RNA polymerase II promoter | TAS | biological_process |
GO:0045892 | negative regulation of transcription, DNA-dependen | IDA | biological_process |
GO:0005515 | protein binding | IPI | molecular_function |
GO:0010629 | negative regulation of gene expression | IDA | biological_process |