Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ZFYV9_HUMAN
Description:zinc finger, FYVE domain containing 9 [Source:HGNC Symbol;Acc:6775]
Location:chr1 p32.3
Node attribute:PPI(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T275ISSQGtDGCPAPhosphoSitePlus
T30ETVSStLLDTKPhosphoSitePlus
T302ISSPRtDLGSPHPRD
S121IKRNYsWDDQCPhosphoSitePlus
S28EDETVsSTLLDPhosphoSitePlus
Y520CYSNIyEQRGNPhosphoSitePlus
S272DSVISsQGTDGPhosphoSitePlus
Y120LIKRNySWDDQPhosphoSitePlus
S271VDSVIsSQGTDPhosphoSitePlus
Y516SKSECySNIYEPhosphoSitePlus
T26QNEDEtVSSTLPhosphoSitePlus
S635NVCSPsLGNISPhosphoSitePlus
S257IGRDPsMSAITPhosphoSitePlus

Dephosphorylation site
ZFYV9_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000287727H1172LCOSMICOvarian Cancer21720365
ENSP00000360647C1405WTCGAOvarian Cancer21720365, 18772890
ENSP00000360647Q6*COSMICMelanoma21499247
ENSP00000287727C1405WTCGAOvarian Cancer21720365, 18772890
ENSP00000360647E988KBIOMARTBreast Cancer21930507, 21930502
ENSP00000287727E988KBIOMARTBreast Cancer21930507, 21930502
ENSP00000360647W1311*COSMICHead and Neck Cancer21798893
ENSP00000360647D479ECOSMICLung Cancer
ENSP00000287727C1405WCOSMICOvarian Cancer21720365
ENSP00000287727D479ECOSMICLung Cancer
ENSP00000360647S1189GCOSMICLung Cancer
ENSP00000360647H1172LCOSMICOvarian Cancer21720365
ENSP00000349737E929KBIOMARTBreast Cancer21930507, 21930502
ENSP00000360647H1172LTCGAOvarian Cancer21720365, 18772890
ENSP00000360647C1405WCOSMICOvarian Cancer21720365
ENSP00000360647S1091NCOSMICSkin Cancer21984974
ENSP00000287727S1189GCOSMICLung Cancer
ENSP00000287727Q6*COSMICMelanoma21499247
ENSP00000287727S1091NCOSMICSkin Cancer21984974
ENSP00000287727H1172LTCGAOvarian Cancer21720365, 18772890
ENSP00000287727W1311*COSMICHead and Neck Cancer21798893

Differential expressed protein
ZFYV9_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ZFYV9_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZFYV9_HUMANSMAD2_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04350TGF-beta signaling pathway
hsa04144Endocytosis

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005737cytoplasmNAScellular_component
GO:0007183SMAD protein complex assemblyIDAbiological_process
GO:0007184SMAD protein import into nucleusIMPbiological_process
GO:0008236serine-type peptidase activityNASmolecular_function
GO:0046872metal ion bindingIEAmolecular_function
GO:0005769early endosomeNAScellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0007179transforming growth factor beta receptor signalingNASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:00055451-phosphatidylinositol bindingIDAmolecular_function
GO:0006897endocytosisNASbiological_process
GO:0030512negative regulation of transforming growth factor TASbiological_process
GO:0031901early endosome membraneIDAcellular_component


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