Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ZBTB4_HUMAN
Description:zinc finger and BTB domain containing 4 [Source:HGNC Symbol;Acc:23847]
Location:chr17 p13.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S687ASVGGsGLPRGPhosphoSitePlus
T266STRGStGLGAGPhosphoSitePlus
S265ASTRGsTGLGAPhosphoSitePlus
S391AFHGIsPGLLAPhosphoSitePlus; HPRD
S105SASSSsSSSSSBTBPhosphoSitePlus
S88AASSSsSSSSSBTBPhosphoSitePlus
S87TAASSsSSSSSBTBPhosphoSitePlus
S104SSASSsSSSSSBTBPhosphoSitePlus
S89ASSSSsSSSSSBTBPhosphoSitePlus
S107SSSSSsSSSSPBTBPhosphoSitePlus
S106ASSSSsSSSSSBTBPhosphoSitePlus
S683AAGGAsVGGSGPhosphoSitePlus
S90SSSSSsSSSSSBTBPhosphoSitePlus
Y415NTLKLyRLLPMPhosphoSitePlus
T797PGGTPtPVIAYPhosphoSitePlus
T795ERPGGtPTPVIPhosphoSitePlus; HPRD
T983PPAPPtPPPPTPhosphoSitePlus

Dephosphorylation site
ZBTB4_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000369973A862VCOSMICMelanoma21499247
ENSP00000369973L879FBIOMARTBreast Cancer21930507, 21930502
ENSP00000369973L948FCOSMICCentral Nervous System Neoplasms18772396
ENSP00000307858S284LBIOMARTBreast Cancer21930507, 21930502
ENSP00000369973R906QCOSMICOvarian Cancer21720365
ENSP00000369973S284LBIOMARTBreast Cancer21930507, 21930502
ENSP00000307858L879FBIOMARTBreast Cancer21930507, 21930502
ENSP00000307858R906QCOSMICOvarian Cancer21720365

Differential expressed protein
ZBTB4_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ZBTB4_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
WEE1_HUMANZBTB4_HUMANkinase -> substrateRobert H Newman (2013)
ST17A_HUMANZBTB4_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
ZBTB4_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005622intracellularIEAcellular_component
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0008270zinc ion bindingIEAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process


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