| UniProt/SwissProt ID: | ZBT17_HUMAN |
| Description: | zinc finger and BTB domain containing 17 [Source:HGNC Symbol;Acc:12936] |
| Location: | chr1 p36.13 |
| Node attribute: | PPI(target); TF |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y362 | SPLKPyGCEEC | zf-C2H2 | PhosphoSitePlus |
| T609 | HIIIHtGEKPY | PhosphoSitePlus | |
| S178 | AQSAAsGAEQT | PhosphoSitePlus | |
| Y371 | ECGKSyRLISL | zf-C2H2 | PhosphoSitePlus |
| T355 | KAHEKtHSPLK | zf-C2H2 | PhosphoSitePlus |
| T274 | EESAGtDSGQE | PhosphoSitePlus | |
| S271 | NENEEsAGTDS | PhosphoSitePlus | |
| T157 | QAGRStPIGPS | PhosphoSitePlus | |
| S276 | SAGTDsGQELG | HPRD | |
| S156 | EQAGRsTPIGP | PhosphoSitePlus | |
| S570 | KRFVQsSQLAN | zf-C2H2 | PhosphoSitePlus |
| S357 | HEKTHsPLKPY | PhosphoSitePlus | |
| T291 | GLRSGtYGDRT | PhosphoSitePlus | |
| S175 | GGQAQsAASGA | PhosphoSitePlus | |
| Dephosphorylation site |
| ZBT17_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000364895 | T635S | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000364885 | Uterine Cancer | Normal vs. Cancer | cell line | Up | 3.6 | 15838902 |
| Hyperphosphorylation site |
| ZBT17_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| MYC_HUMAN | ZBT17_HUMAN | other | KEGG |
| ZBT17_HUMAN | CDN2B_HUMAN | TF -> target gene | KEGG |
| ZBT17_HUMAN | CDN1A_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa05202 | Transcriptional misregulation in cancer |
| hsa04110 | Cell cycle |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0030968 | endoplasmic reticulum unfolded protein response | TAS | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0007398 | ectoderm development | IEA | biological_process |
| GO:0005654 | nucleoplasm | TAS | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0008270 | zinc ion binding | IEA | molecular_function |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0045786 | negative regulation of cell cycle | TAS | biological_process |
| GO:0045893 | positive regulation of transcription, DNA-dependen | IEA | biological_process |
| GO:0003700 | sequence-specific DNA binding transcription factor | IDA | molecular_function |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0001702 | gastrulation with mouth forming second | IEA | biological_process |
| GO:0006987 | activation of signaling protein activity involved | TAS | biological_process |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |