| UniProt/SwissProt ID: | XPR1_HUMAN |
| Description: | xenotropic and polytropic retrovirus receptor 1 [Source:HGNC Symbol;Acc:12827] |
| Location: | chr1 q25.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T574 | LRFAWtIQISI | EXS | PhosphoSitePlus |
| Y50 | DTVKRyFAKFE | HPRD | |
| Y73 | KINTFySEKLA | SPX | PhosphoSitePlus |
| T690 | VLIEDtDDEA | HPRD | |
| S660 | RQKNRsWKYNQ | PhosphoSitePlus | |
| T696 | DDEA | HPRD | |
| T594 | GDIIAtVFAPL | EXS | PhosphoSitePlus |
| T498 | AALYStHKERG | EXS | PhosphoSitePlus |
| T105 | ESTGVtTLRQR | SPX | PhosphoSitePlus |
| Y663 | NRSWKyNQSIS | PhosphoSitePlus | |
| S676 | RPRLAsQSKAR | PhosphoSitePlus | |
| S668 | YNQSIsLRRPR | PhosphoSitePlus; HPRD | |
| Y483 | VNAGKySTTFF | EXS; TM | PhosphoSitePlus |
| T106 | STGVTtLRQRR | SPX | PhosphoSitePlus |
| S666 | WKYNQsISLRR | PhosphoSitePlus; HPRD | |
| T690 | VLIEDtDDEAN | PhosphoSitePlus | |
| Dephosphorylation site |
| XPR1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000356562 | R611H | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| XPR1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| XPR1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| FGFR1_HUMAN | XPR1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| XPR1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0004872 | receptor activity | IEA | molecular_function |
| GO:0004888 | transmembrane signaling receptor activity | TAS | molecular_function |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0004930 | G-protein coupled receptor activity | TAS | molecular_function |
| GO:0009615 | response to virus | IEA | biological_process |
| GO:0004872 | receptor activity | TAS | molecular_function |
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |