Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:WASF1_HUMAN
Description:WAS protein family, member 1 [Source:HGNC Symbol;Acc:12732]
Location:chr6 q21
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S91KEEELsLQDITPhosphoSitePlus; HPRD
S489PKRHPsTLPVIPhosphoSitePlus
Y125PLQETyDVCEQSrcRegPhos
S339ALSTSsLRASMPhosphoSitePlus
S441GIRPSsPVTVTCDK5HPRD
S397PLVQPsPPVARCDK5HPRD
Y125PLQETyDVCEQSRCphosphoELM
Y125PLQETyDVCEQPhosphoSitePlus
S298IPTCIsSATGLHPRD
T490KRHPStLPVISPhosphoSitePlus
S310ENRPQsPATGRPhosphoSitePlus
S310ENRPQsPATGRCDK5HPRD
T96SLQDItMRKAFPhosphoSitePlus; HPRD

Dephosphorylation site
WASF1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000376365Q110*COSMICHead and Neck Cancer21798893

Differential expressed protein
WASF1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
WASF1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CDK5_HUMANWASF1_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04520Adherens junction
hsa04666Fc gamma R-mediated phagocytosis
hsa05132Salmonella infection
hsa04810Regulation of actin cytoskeleton
hsa05131Shigellosis
hsa05100Bacterial invasion of epithelial cells

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIEAmolecular_function
GO:0015629actin cytoskeletonTAScellular_component
GO:0005741mitochondrial outer membraneIEAcellular_component
GO:0005739mitochondrionIEAcellular_component
GO:0006928cellular component movementTASbiological_process
GO:0030041actin filament polymerizationTASbiological_process
GO:0030027lamellipodiumIEAcellular_component
GO:0005856cytoskeletonTAScellular_component
GO:0006461protein complex assemblyNASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0003779actin bindingIEAmolecular_function


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