Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:VEGFD_HUMAN
Description:c-fos induced growth factor (vascular endothelial growth factor D) [Source:HGNC Symbol;Acc:3708]
Location:chrX p22.2
Node attribute:PPI(source); ligand; gene

Phosphorylation site
VEGFD_HUMAN do not have phosphorylation site.

Dephosphorylation site
VEGFD_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000297904Q346*COSMICSkin Cancer21984974
ENSP00000297904K232ECOSMICCentral Nervous System Neoplasms18772396
ENSP00000297904E177KCOSMICBreast Cancer
ENSP00000297904H308YBIOMARTBreast Cancer21930507, 21930502
ENSP00000297904P135SCOSMICOvarian Cancer21720365

Differential expressed protein
VEGFD_HUMAN is not differential expressed protein.

Hyperphosphorylation site
VEGFD_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
VEGFD_HUMANNRP2_HUMANligand -> receptorHPMR
VEGFD_HUMANVGFR3_HUMANligand -> receptorHPMR
VEGFD_HUMANVGFR2_HUMANotherKEGG
VEGFD_HUMANVGFR3_HUMANotherKEGG
HIF1A_HUMANVEGFD_HUMANTF -> target geneKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05211Renal cell carcinoma
hsa05212Pancreatic cancer
hsa05200Pathways in cancer
hsa05219Bladder cancer
hsa04510Focal adhesion
hsa04060Cytokine-cytokine receptor interaction
hsa04150mTOR signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIEAmolecular_function
GO:0005576extracellular regionTAScellular_component
GO:0005615extracellular spaceIEAcellular_component
GO:0031093platelet alpha granule lumenTAScellular_component
GO:0048010vascular endothelial growth factor receptor signalIEAbiological_process
GO:0051781positive regulation of cell divisionIEAbiological_process
GO:0030154cell differentiationIEAbiological_process
GO:0008283cell proliferationIEAbiological_process
GO:0002576platelet degranulationTASbiological_process
GO:0050918positive chemotaxisIDAbiological_process
GO:0042056chemoattractant activityIDAmolecular_function
GO:0043185vascular endothelial growth factor receptor 3 bindIEAmolecular_function
GO:0005172vascular endothelial growth factor receptor bindinIPImolecular_function
GO:0060754positive regulation of mast cell chemotaxisIDAbiological_process
GO:0048010vascular endothelial growth factor receptor signalTASbiological_process
GO:0030168platelet activationTASbiological_process
GO:0001525angiogenesisIEAbiological_process
GO:0005161platelet-derived growth factor receptor bindingTASmolecular_function
GO:0042803protein homodimerization activityIEAmolecular_function
GO:0008284positive regulation of cell proliferationIEAbiological_process
GO:0008083growth factor activityIEAmolecular_function
GO:0005576extracellular regionIEAcellular_component
GO:0016020membraneIEAcellular_component
GO:0050930induction of positive chemotaxisIDAbiological_process
GO:0007596blood coagulationTASbiological_process


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