Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:NRP2_HUMAN
Description:neuropilin 2 [Source:HGNC Symbol;Acc:8005]
Location:chr2 q33.3
Node attribute:receptor

Phosphorylation site
NRP2_HUMAN do not have phosphorylation site.

Dephosphorylation site
NRP2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000353582W754LCOSMICHead and Neck Cancer21984974
ENSP00000349632E351*BIOMARTBreast Cancer21930507, 21930502
ENSP00000272849E351*BIOMARTBreast Cancer21930507, 21930502
ENSP00000353582R310QCOSMICHead and Neck Cancer21798893
ENSP00000353582T861ICOSMICMelanoma21499247
ENSP00000272849A98TBIOMARTHepatocellular Carcinoma21930507, 21930502
ENSP00000353582E351*BIOMARTBreast Cancer21930507, 21930502
ENSP00000350432E351*BIOMARTBreast Cancer21930507, 21930502
ENSP00000407626E351*BIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000353582Testicular CancerNormal vs. Cancercell lineUp18489135

Hyperphosphorylation site
NRP2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
SEM3C_HUMANNRP2_HUMANligand -> receptorHPMR
VEGFD_HUMANNRP2_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
NRP2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0016021integral to membraneNAScellular_component
GO:0071526semaphorin-plexin signaling pathwayIEAbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0030424axonIEAcellular_component
GO:0017154semaphorin receptor activityIEAmolecular_function
GO:0008201heparin bindingIEAmolecular_function
GO:0005021vascular endothelial growth factor-activated recepNASmolecular_function
GO:0016020membraneTAScellular_component
GO:0002116semaphorin receptor complexNAScellular_component
GO:0019838growth factor bindingTASmolecular_function
GO:0050919negative chemotaxisIEAbiological_process
GO:0038084vascular endothelial growth factor signaling pathwNASbiological_process
GO:0001525angiogenesisNASbiological_process
GO:0004872receptor activityTASmolecular_function
GO:0048010vascular endothelial growth factor receptor signalTASbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0007411axon guidanceIEAbiological_process
GO:0019955cytokine bindingNASmolecular_function
GO:0007507heart developmentIEAbiological_process
GO:0046872metal ion bindingIEAmolecular_function
GO:0005576extracellular regionIEAcellular_component
GO:0007155cell adhesionNASbiological_process
GO:0010595positive regulation of endothelial cell migrationTASbiological_process
GO:0001938positive regulation of endothelial cell proliferatTASbiological_process
GO:0001755neural crest cell migrationIEAbiological_process


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23