| UniProt/SwissProt ID: | VAMP4_HUMAN |
| Description: | vesicle-associated membrane protein 4 [Source:HGNC Symbol;Acc:12645] |
| Location: | chr1 q24.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S17 | DDVTGsVKSER | PhosphoSitePlus; HPRD; SysPTM | |
| S88 | ELQDKsESLSD | HPRD | |
| S90 | QDKSEsLSDNA | HPRD | |
| S30 | LLEDDsDEEED | CSNK2A1 | HPRD; SysPTM |
| S30 | LLEDDsDEEED | CK2_group | phosphoELM; RegPhos; SysPTM |
| S42 | FLRGPsGPRFG | HPRD; SysPTM | |
| S88 | ELQDKsESLSD | Synaptobrevin | PhosphoSitePlus |
| S90 | QDKSEsLSDNA | Synaptobrevin | PhosphoSitePlus |
| S30 | LLEDDsDEEED | CK2a1 | RegPhos; SysPTM |
| S30 | LLEDDsDEEED | CK2a1-rs | RegPhos; SysPTM |
| Y139 | LIVMKyRT___ | PhosphoSitePlus | |
| S30 | LLEDDsDEEED | PhosphoSitePlus; phosphoELM; RegPhos; SysPTM | |
| Dephosphorylation site |
| VAMP4_HUMAN do not have dephosphorylation site. |
| Mutation site |
| VAMP4_HUMAN do not have mutation site. |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000236192 | Testicular Cancer | Normal vs. Cancer | cell line | Down | 18489135 | |
| Hyperphosphorylation site |
| VAMP4_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ZAGL2_HUMAN | VAMP4_HUMAN | kinase -> substrate | RegPhos |
| CSK21_HUMAN | VAMP4_HUMAN | kinase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04130 | SNARE interactions in vesicular transport |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005802 | trans-Golgi network | IEA | cellular_component |
| GO:0043001 | Golgi to plasma membrane protein transport | IEA | biological_process |
| GO:0016192 | vesicle-mediated transport | IEA | biological_process |
| GO:0031201 | SNARE complex | IEA | cellular_component |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0005768 | endosome | TAS | cellular_component |
| GO:0005764 | lysosome | TAS | cellular_component |
| GO:0000139 | Golgi membrane | TAS | cellular_component |
| GO:0042996 | regulation of Golgi to plasma membrane protein tra | IEA | biological_process |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |