| UniProt/SwissProt ID: | UD2B7_HUMAN |
| Description: | UDP glucuronosyltransferase 2 family, polypeptide B7 [Source:HGNC Symbol;Acc:12554] |
| Location: | chr4 q13.2 |
| Node attribute: | gene |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y236 | KWDQFySEVLG | UDPGT | PhosphoSitePlus |
| Y438 | INDPSyKENVM | UDPGT | PhosphoSitePlus |
| Dephosphorylation site |
| UD2B7_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000304811 | E225K | COSMIC | Skin Cancer | 21984974 | ENSP00000304811 | G526V | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000304811 | S61F | COSMIC | Melanoma | 21499247 |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000304811 | Renal Cancer | Normal vs. Cancer | tissue | Down | 19164279 | |
| Hyperphosphorylation site |
| UD2B7_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| HNF1A_HUMAN | UD2B7_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| UD2B7_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0016020 | membrane | TAS | cellular_component |
| GO:0005975 | carbohydrate metabolic process | IEA | biological_process |
| GO:0005789 | endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0016758 | transferase activity, transferring hexosyl groups | IEA | molecular_function |
| GO:0006629 | lipid metabolic process | TAS | biological_process |
| GO:0052695 | cellular glucuronidation | IDA | biological_process |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0030259 | lipid glycosylation | IEA | biological_process |
| GO:0015020 | glucuronosyltransferase activity | IDA | molecular_function |
| GO:0008152 | metabolic process | IEA | biological_process |
| GO:0030246 | carbohydrate binding | IEA | molecular_function |
| GO:0008209 | androgen metabolic process | IDA | biological_process |