Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:UBE2B_HUMAN
Description:ubiquitin-conjugating enzyme E2B [Source:HGNC Symbol;Acc:12473]
Location:chr5 q31.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S120EPNPNsPANSQHPRD

Dephosphorylation site
UBE2B_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000265339P47TBIOMARTHepatocellular Carcinoma21930507, 21930502

Differential expressed protein
UBE2B_HUMAN is not differential expressed protein.

Hyperphosphorylation site
UBE2B_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KPCD_HUMANUBE2B_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
UBE2B_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005524ATP bindingIEAmolecular_function
GO:0001666response to hypoxiaIEAbiological_process
GO:0005886plasma membraneIEAcellular_component
GO:0070076histone lysine demethylationIEAbiological_process
GO:0060070canonical Wnt receptor signaling pathwayIEAbiological_process
GO:0043161proteasomal ubiquitin-dependent protein catabolic IDAbiological_process
GO:0001701in utero embryonic developmentIEAbiological_process
GO:0006974response to DNA damage stimulusIDAbiological_process
GO:0005634nucleusIDAcellular_component
GO:0070193synaptonemal complex organizationIEAbiological_process
GO:0010845positive regulation of reciprocal meiotic recombinIEAbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0006511ubiquitin-dependent protein catabolic processIEAbiological_process
GO:0006281DNA repairIGIbiological_process
GO:0051865protein autoubiquitinationIDAbiological_process
GO:0051026chiasma assemblyIEAbiological_process
GO:0031056regulation of histone modificationIEAbiological_process
GO:0033503HULC complexIDAcellular_component
GO:0070936protein K48-linked ubiquitinationIDAbiological_process
GO:0000209protein polyubiquitinationIMPbiological_process
GO:0016567protein ubiquitinationIDAbiological_process
GO:0000785chromatinISScellular_component
GO:0070534protein K63-linked ubiquitinationIDAbiological_process
GO:0032869cellular response to insulin stimulusIEAbiological_process
GO:0033522histone H2A ubiquitinationIMPbiological_process
GO:0050821protein stabilizationIMPbiological_process
GO:0043951negative regulation of cAMP-mediated signalingIDAbiological_process
GO:0033128negative regulation of histone phosphorylationIEAbiological_process
GO:0007288sperm axoneme assemblyIEAbiological_process
GO:0060070canonical Wnt receptor signaling pathwayISSbiological_process
GO:0016881acid-amino acid ligase activityIEAmolecular_function
GO:0070979protein K11-linked ubiquitinationIDAbiological_process
GO:0001741XY bodyIEAcellular_component
GO:0007283spermatogenesisIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0000785chromatinIEAcellular_component
GO:0007283spermatogenesisTASbiological_process
GO:0006511ubiquitin-dependent protein catabolic processIDAbiological_process
GO:0006301postreplication repairIDAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0004842ubiquitin-protein ligase activityIDAmolecular_function
GO:0006344maintenance of chromatin silencingIEAbiological_process
GO:0006513protein monoubiquitinationIMPbiological_process
GO:0005657replication forkIDAcellular_component
GO:0031625ubiquitin protein ligase bindingIPImolecular_function
GO:0009411response to UVIGIbiological_process
GO:0043066negative regulation of apoptotic processIEAbiological_process
GO:0042493response to drugIDAbiological_process
GO:0000790nuclear chromatinIEAcellular_component


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23