Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:UB2D3_HUMAN
Description:ubiquitin-conjugating enzyme E2D 3 [Source:HGNC Symbol;Acc:12476]
Location:chr4 q24
Node attribute:ubiquitination(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y145EWTQKyAM___PhosphoSitePlus
S9NRKCLsKELSDHPRD
S13LSKELsDLARDHPRD

Dephosphorylation site
UB2D3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000349722*150LCOSMICHead and Neck Cancer21798893

Differential expressed protein
UB2D3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
UB2D3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
UB2D3_HUMANIKBA_HUMANubiquitinationNetPath
UB2D3_HUMANNFKB1_HUMANubiquitinationNetPath

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04141Protein processing in endoplasmic reticulum
hsa04120Ubiquitin mediated proteolysis

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0071456cellular response to hypoxiaTASbiological_process
GO:0006281DNA repairIEAbiological_process
GO:0043161proteasomal ubiquitin-dependent protein catabolic IDAbiological_process
GO:0045087innate immune responseTASbiological_process
GO:0005886plasma membraneIEAcellular_component
GO:0005654nucleoplasmTAScellular_component
GO:0030509BMP signaling pathwayTASbiological_process
GO:0070979protein K11-linked ubiquitinationIDAbiological_process
GO:0006513protein monoubiquitinationIDAbiological_process
GO:0005829cytosolTAScellular_component
GO:0000209protein polyubiquitinationIDAbiological_process
GO:0006351transcription, DNA-dependentTASbiological_process
GO:0004842ubiquitin-protein ligase activityIDAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0016567protein ubiquitinationIDAbiological_process
GO:0032480negative regulation of type I interferon productioTASbiological_process
GO:0070936protein K48-linked ubiquitinationIDAbiological_process
GO:0016881acid-amino acid ligase activityIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0006464cellular protein modification processTASbiological_process
GO:0007179transforming growth factor beta receptor signalingTASbiological_process
GO:0010008endosome membraneIEAcellular_component
GO:0006915apoptotic processIEAbiological_process
GO:0010467gene expressionTASbiological_process
GO:0061418regulation of transcription from RNA polymerase IITASbiological_process
GO:0006367transcription initiation from RNA polymerase II prTASbiological_process
GO:0033554cellular response to stressTASbiological_process
GO:0006511ubiquitin-dependent protein catabolic processTASbiological_process
GO:0000122negative regulation of transcription from RNA polyTASbiological_process


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