| UniProt/SwissProt ID: | U2AFM_HUMAN |
| Description: | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 [Source:HGNC Symbol;Acc:23019] |
| Location: | chrX p22.2 |
| Node attribute: | gene |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S349 | RDIYLsPDRTG | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| Y374 | HHDDYySRLRG | PhosphoSitePlus | |
| S388 | PSPDHsYKRNG | HPRD | |
| S384 | GRRNPsPDHSY | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| Y389 | SPDHSyKRNGE | HPRD | |
| T207 | IKSMFtTFGME | PhosphoSitePlus | |
| S356 | NPNNEFWEANRDIYLSPDRTGSSFGK | SysPTM 2.0 | |
| S355 | NPNNEFWEANRDIYLSPDRTGSSFGK | SysPTM 2.0 | |
| S355 | NPNNEFWEANRDIYLSPDRTGSSFGK | SysPTM 2.0 | |
| Dephosphorylation site |
| U2AFM_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000303015 | A95G | COSMIC | Breast Cancer | 20393555 |
| Differential expressed protein |
| U2AFM_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| U2AFM_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| SP1_HUMAN | U2AFM_HUMAN | TF -> target gene | TRANSFAC |
| PO2F1_HUMAN | U2AFM_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| U2AFM_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0030628 | pre-mRNA 3'-splice site binding | IDA | molecular_function |
| GO:0005689 | U12-type spliceosomal complex | IDA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0008270 | zinc ion binding | IEA | molecular_function |
| GO:0000398 | mRNA splicing, via spliceosome | IMP | biological_process |
| GO:0003676 | nucleic acid binding | IEA | molecular_function |
| GO:0008380 | RNA splicing | IC | biological_process |
| GO:0000245 | spliceosomal complex assembly | IMP | biological_process |
| GO:0000166 | nucleotide binding | IEA | molecular_function |