| UniProt/SwissProt ID: | TYY1_HUMAN |
| Description: | YY1 transcription factor [Source:HGNC Symbol;Acc:12856] |
| Location: | chr14 q32.2 |
| Node attribute: | TF |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S165 | GGGGSsSSGGG | PhosphoSitePlus | |
| T348 | HQLVHtGEKPF | HPRD; phosphoELM; SysPTM | |
| S180 | GGGKKsGKKSY | PhosphoSitePlus | |
| S247 | IIGENsPPDYS | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| T378 | HVRIHtGDRPY | Raffinose_syn; zf-H2C2_2 | PhosphoSitePlus; SysPTM |
| S365 | CGKRFsLDFNL | Raffinose_syn; zf-H2C2_2 | PhosphoSitePlus |
| T348 | HQLVHtGEKPF | IBR; Raffinose_syn; zf-H2 | PhosphoSitePlus; SysPTM |
| Y251 | NSPPDySEYMT | PhosphoSitePlus; HPRD; phosphoELM | |
| Y254 | PDYSEyMTGKK | PhosphoSitePlus | |
| S187 | KKSYLsGGAGA | PhosphoSitePlus | |
| S184 | KSGKKsYLSGG | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| S365 | CGKRFsLDFNL | HPRD | |
| Y185 | SGKKSyLSGGA | PhosphoSitePlus | |
| T378 | HVRIHtGDRPY | HPRD; phosphoELM; SysPTM | |
| T39 | ETIETtVVGEE | GRP | PhosphoSitePlus |
| S118 | VGGDDsDGLRA | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| Dephosphorylation site |
| TYY1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000262238 | G361E | COSMIC | Skin Cancer | 21984974 |
| Differential expressed protein |
| TYY1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| TYY1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| TYY1_HUMAN | DMD_HUMAN | TF -> target gene | TRANSFAC |
| TYY1_HUMAN | P53_HUMAN | TF -> target gene | TRANSFAC |
| TYY1_HUMAN | IFNG_HUMAN | TF -> target gene | TRANSFAC |
| TYY1_HUMAN | DOPO_HUMAN | TF -> target gene | TRANSFAC |
| TYY1_HUMAN | HBE_HUMAN | TF -> target gene | TRANSFAC |
| TYY1_HUMAN | FOS_HUMAN | TF -> target gene | TRANSFAC |
| TYY1_HUMAN | IFNA7_HUMAN | TF -> target gene | TRANSFAC |
| TYY1_HUMAN | CSF2_HUMAN | TF -> target gene | TRANSFAC |
| TYY1_HUMAN | ARY1_HUMAN | TF -> target gene | TRANSFAC |
| TYY1_HUMAN | SURF1_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| TYY1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0003713 | transcription coactivator activity | TAS | molecular_function |
| GO:0034696 | response to prostaglandin F stimulus | IEA | biological_process |
| GO:0000400 | four-way junction DNA binding | IDA | molecular_function |
| GO:0005886 | plasma membrane | IDA | cellular_component |
| GO:0030154 | cell differentiation | IEA | biological_process |
| GO:0006974 | response to DNA damage stimulus | IEA | biological_process |
| GO:0007283 | spermatogenesis | IEA | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0000724 | double-strand break repair via homologous recombin | IMP | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |
| GO:0001078 | RNA polymerase II core promoter proximal region se | ISS | molecular_function |
| GO:0000122 | negative regulation of transcription from RNA poly | IEA | biological_process |
| GO:0006403 | RNA localization | IEA | biological_process |
| GO:0051276 | chromosome organization | IEA | biological_process |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0003700 | sequence-specific DNA binding transcription factor | IEA | molecular_function |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0031519 | PcG protein complex | IEA | cellular_component |
| GO:0009952 | anterior/posterior pattern specification | IEA | biological_process |
| GO:0006357 | regulation of transcription from RNA polymerase II | TAS | biological_process |
| GO:0044212 | transcription regulatory region DNA binding | IDA | molecular_function |
| GO:0031011 | Ino80 complex | IDA | cellular_component |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0010225 | response to UV-C | IEA | biological_process |
| GO:0008270 | zinc ion binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IDA | molecular_function |
| GO:0016363 | nuclear matrix | IEA | cellular_component |
| GO:0034644 | cellular response to UV | IMP | biological_process |
| GO:0048593 | camera-type eye morphogenesis | IEA | biological_process |
| GO:0003714 | transcription corepressor activity | TAS | molecular_function |
| GO:0005667 | transcription factor complex | IEA | cellular_component |