Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TUT4_HUMAN
Description:zinc finger, CCHC domain containing 11 [Source:HGNC Symbol;Acc:28981]
Location:chr1 p32.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S831LKKELsQCNCIPhosphoSitePlus; HPRD
T1101QYLGYtMKVFAPhosphoSitePlus
S678IEDPFsVKRNVPAP_assocPhosphoSitePlus
S847PDPDKsTGTDCPhosphoSitePlus
S356HLAALsVAVIEPhosphoSitePlus
S134EKSPKsPNSVKPhosphoSitePlus
S343ESELRsLPPPSPhosphoSitePlus
S137PKSPNsVKAEKPhosphoSitePlus
S574KWECNsSSATEPhosphoSitePlus
S773EMDCTsQRCIIPhosphoSitePlus; HPRD; phosphoELM
Y1100VQYLGyTMKVFPhosphoSitePlus
T217SQKQQtCTDNTPhosphoSitePlus
T848DPDKStGTDCRPhosphoSitePlus; HPRD
S1384RQRNSsVAAAQPhosphoSitePlus
Y1097DPRVQyLGYTMPhosphoSitePlus
S348SLPPPsPAHLAPhosphoSitePlus
S104KKFPNsPVKAEPhosphoSitePlus
T850DKSTGtDCRSNPhosphoSitePlus; HPRD
S1383ARQRNsSVAAAPhosphoSitePlus
S156EKVPSsPAEAEPhosphoSitePlus

Dephosphorylation site
TUT4_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000257177F1147LCOSMICMelanoma21499247
ENSP00000257177N744SCOSMICOvarian Cancer21720365
ENSP00000257177Q1446*BIOMARTBreast Cancer21930507, 21930502
ENSP00000360599Q1445*BIOMARTBreast Cancer21930507, 21930502
ENSP00000360599Q1151HBIOMARTBreast Cancer21930507, 21930502
ENSP00000257177Q1151HBIOMARTBreast Cancer21930507, 21930502
ENSP00000257177R461QBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000360599R461QBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000257177G1286ECOSMICHead and Neck Cancer21798893
ENSP00000348063*310SCOSMICOvarian Cancer21720365
ENSP00000257177P495LCOSMICSkin Cancer21984974

Differential expressed protein
TUT4_HUMAN is not differential expressed protein.

Hyperphosphorylation site
TUT4_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
FYN_HUMANTUT4_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
TUT4_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0070102interleukin-6-mediated signaling pathwayIEAbiological_process
GO:0016779nucleotidyltransferase activityIEAmolecular_function
GO:0032755positive regulation of interleukin-6 productionIEAbiological_process
GO:0032088negative regulation of NF-kappaB transcription facIEAbiological_process
GO:0031054pre-miRNA processingIMPbiological_process
GO:0008270zinc ion bindingIEAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0031123RNA 3'-end processingIDAbiological_process
GO:0031664regulation of lipopolysaccharide-mediated signalinIEAbiological_process
GO:0050265RNA uridylyltransferase activityIDAmolecular_function
GO:0005730nucleolusIDAcellular_component
GO:0010586miRNA metabolic processIEAbiological_process
GO:0001816cytokine productionIEAbiological_process
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0005737cytoplasmIEAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0010587miRNA catabolic processIMPbiological_process
GO:0019827stem cell maintenanceIMPbiological_process


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