| UniProt/SwissProt ID: | TULP4_HUMAN |
| Description: | tubby like protein 4 [Source:HGNC Symbol;Acc:15530] |
| Location: | chr6 q25.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y1068 | ASQSSySLLSP | PhosphoSitePlus | |
| S1343 | RKRLDsRAEEG | API5 | PhosphoSitePlus |
| Y366 | SGPALyVVRVE | PhosphoSitePlus | |
| Y873 | GDFSLyPTSVH | PhosphoSitePlus | |
| S1060 | HTASAsPLASQ | PhosphoSitePlus | |
| S577 | KPSVGsPSLTR | PhosphoSitePlus | |
| Y626 | LGAVIyKTSLL | PhosphoSitePlus | |
| S574 | PLRKPsVGSPS | PhosphoSitePlus | |
| Y879 | PTSVHyQTPLG | PhosphoSitePlus | |
| Dephosphorylation site |
| TULP4_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000356064 | K541E | COSMIC | Ovarian Cancer | 21720365 | ENSP00000356064 | M1187V | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000356064 | E391K | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000356061 | K541E | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000356064 | A1362P | BIOMART | Gastric Cancer | 21930507, 21930502 |
| Differential expressed protein |
| TULP4_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| TULP4_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| EF2K_HUMAN | TULP4_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| TULP4_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0035556 | intracellular signal transduction | IEA | biological_process |
| GO:0007584 | response to nutrient | TAS | biological_process |
| GO:0016567 | protein ubiquitination | IEA | biological_process |
| GO:0006355 | regulation of transcription, DNA-dependent | NAS | biological_process |
| GO:0003700 | sequence-specific DNA binding transcription factor | NAS | molecular_function |
| GO:0005515 | protein binding | IEA | molecular_function |