Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TRI18_HUMAN
Description:midline 1 (Opitz/BBB syndrome) [Source:HGNC Symbol;Acc:7095]
Location:chrX p22.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S98GPNSPsETRREPhosphoSitePlus; HPRD; phosphoELM
S90RFQKAsVSGPNHPRD
T518SKKSHtPERFTPhosphoSitePlus
S572WIGKNsASWALSPRYPhosphoSitePlus
S500RKLKVsHDNLTPhosphoSitePlus
Y528TSQGSyGVAGNPhosphoSitePlus
S92QKASVsGPNSPPhosphoSitePlus; HPRD; phosphoELM
S513RDESSsKKSHTPhosphoSitePlus
S96VSGPNsPSETRPhosphoSitePlus; HPRD; phosphoELM

Dephosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S96ASVSGPNsPSETRREPPP2CBHPRD

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000370164D435NBIOMARTBreast Cancer21930507, 21930502
ENSP00000370164W584CCOSMICPancreatic Cancer
ENSP00000312678D435NBIOMARTBreast Cancer21930507, 21930502
ENSP00000370164A394PCOSMICOvarian Cancer21720365
ENSP00000370159D435NBIOMARTBreast Cancer21930507, 21930502
ENSP00000370156D435NBIOMARTBreast Cancer21930507, 21930502
ENSP00000370162E271QCOSMICOvarian Cancer21720365
ENSP00000370156K303ECOSMICHead and Neck Cancer21798893
ENSP00000414521K303ECOSMICHead and Neck Cancer21798893
ENSP00000414521A394PCOSMICOvarian Cancer21720365
ENSP00000414521D435NBIOMARTBreast Cancer21930507, 21930502
ENSP00000370157L21FCOSMICSkin Cancer21984974
ENSP00000414521E271QCOSMICOvarian Cancer21720365
ENSP00000414521W584CCOSMICPancreatic Cancer
ENSP00000370156E271QCOSMICOvarian Cancer21720365
ENSP00000370157K303ECOSMICHead and Neck Cancer21798893
ENSP00000312678E271QCOSMICOvarian Cancer21720365
ENSP00000370157W584CCOSMICPancreatic Cancer
ENSP00000370156W584CCOSMICPancreatic Cancer
ENSP00000370156A394PCOSMICOvarian Cancer21720365
ENSP00000414521L21FCOSMICSkin Cancer21984974
ENSP00000370162D435NBIOMARTBreast Cancer21930507, 21930502
ENSP00000370162W584CCOSMICPancreatic Cancer
ENSP00000312678K303ECOSMICHead and Neck Cancer21798893
ENSP00000312678A394PCOSMICOvarian Cancer21720365
ENSP00000370164L21FCOSMICSkin Cancer21984974
ENSP00000370162K303ECOSMICHead and Neck Cancer21798893
ENSP00000370162L21FCOSMICSkin Cancer21984974
ENSP00000312678L21FCOSMICSkin Cancer21984974
ENSP00000370164E271QCOSMICOvarian Cancer21720365
ENSP00000370157A394PCOSMICOvarian Cancer21720365
ENSP00000370157D435NBIOMARTBreast Cancer21930507, 21930502
ENSP00000312678W584CCOSMICPancreatic Cancer
ENSP00000370156L21FCOSMICSkin Cancer21984974
ENSP00000370162A394PCOSMICOvarian Cancer21720365
ENSP00000370157E271QCOSMICOvarian Cancer21720365
ENSP00000370164K303ECOSMICHead and Neck Cancer21798893

Differential expressed protein
TRI18_HUMAN is not differential expressed protein.

Hyperphosphorylation site
TRI18_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PP2AB_HUMANTRI18_HUMANphosphatase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04120Ubiquitin mediated proteolysis

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0008270zinc ion bindingIEAmolecular_function
GO:0000226microtubule cytoskeleton organizationTASbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0005881cytoplasmic microtubuleIDAcellular_component
GO:0005819spindleIEAcellular_component
GO:0032874positive regulation of stress-activated MAPK cascaIMPbiological_process
GO:0005622intracellularIEAcellular_component
GO:0031625ubiquitin protein ligase bindingIPImolecular_function
GO:0007389pattern specification processTASbiological_process
GO:0016874ligase activityIEAmolecular_function
GO:0005875microtubule associated complexTAScellular_component


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