Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TRI16_HUMAN
Description:tripartite motif containing 16 [Source:HGNC Symbol;Acc:17241]
Location:chr17 p12
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S60TEEQDsDSAEQPhosphoSitePlus; HPRD; phosphoELM; SysPTM
Y531FSEPVyAAFWLSPRYPhosphoSitePlus
Y341SKEEEyDIRTQPhosphoSitePlus
Y430YLHRYyFEVEISPRYPhosphoSitePlus
S537AAFWLsKKENAHPRD
Y531FSEPVyAAFWLHPRD
S537AAFWLsKKENASPRYPhosphoSitePlus
T55KLGREtEEQDSPhosphoSitePlus; HPRD; SysPTM
Y441FGAGTyVGLTCSPRYPhosphoSitePlus
S62EQDSDsAEQGDHPRD; SysPTM
Y429LYLHRyYFEVESPRYPhosphoSitePlus

Dephosphorylation site
TRI16_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000338989S308*COSMICOvarian Cancer21720365
ENSP00000338989V123MCOSMICMelanoma
ENSP00000338989Q421*COSMICSkin Cancer21984974
ENSP00000338989D342YCOSMICOvarian Cancer21720365

Differential expressed protein
TRI16_HUMAN is not differential expressed protein.

Hyperphosphorylation site
TRI16_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
LCK_HUMANTRI16_HUMANkinase -> substrateRobert H Newman (2013)
PKN1_HUMANTRI16_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
TRI16_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIPImolecular_function
GO:0016605PML bodyIDAcellular_component
GO:0032089NACHT domain bindingIPImolecular_function
GO:0046683response to organophosphorusIEPbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0019966interleukin-1 bindingIPImolecular_function
GO:0048386positive regulation of retinoic acid receptor signIDAbiological_process
GO:0045618positive regulation of keratinocyte differentiatioIDAbiological_process
GO:0043966histone H3 acetylationIDAbiological_process
GO:0060416response to growth hormone stimulusIDAbiological_process
GO:0050718positive regulation of interleukin-1 beta secretioIMPbiological_process
GO:0003677DNA bindingIDAmolecular_function
GO:0045893positive regulation of transcription, DNA-dependenIDAbiological_process
GO:0032526response to retinoic acidIEPbiological_process
GO:0008270zinc ion bindingIEAmolecular_function
GO:0043967histone H4 acetylationIDAbiological_process
GO:0005622intracellularIEAcellular_component


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