| UniProt/SwissProt ID: | TRI16_HUMAN |
| Description: | tripartite motif containing 16 [Source:HGNC Symbol;Acc:17241] |
| Location: | chr17 p12 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S60 | TEEQDsDSAEQ | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| Y531 | FSEPVyAAFWL | SPRY | PhosphoSitePlus |
| Y341 | SKEEEyDIRTQ | PhosphoSitePlus | |
| Y430 | YLHRYyFEVEI | SPRY | PhosphoSitePlus |
| S537 | AAFWLsKKENA | HPRD | |
| Y531 | FSEPVyAAFWL | HPRD | |
| S537 | AAFWLsKKENA | SPRY | PhosphoSitePlus |
| T55 | KLGREtEEQDS | PhosphoSitePlus; HPRD; SysPTM | |
| Y441 | FGAGTyVGLTC | SPRY | PhosphoSitePlus |
| S62 | EQDSDsAEQGD | HPRD; SysPTM | |
| Y429 | LYLHRyYFEVE | SPRY | PhosphoSitePlus |
| Dephosphorylation site |
| TRI16_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000338989 | S308* | COSMIC | Ovarian Cancer | 21720365 | ENSP00000338989 | V123M | COSMIC | Melanoma | ENSP00000338989 | Q421* | COSMIC | Skin Cancer | 21984974 | ENSP00000338989 | D342Y | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| TRI16_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| TRI16_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| LCK_HUMAN | TRI16_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| PKN1_HUMAN | TRI16_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| TRI16_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0016605 | PML body | IDA | cellular_component |
| GO:0032089 | NACHT domain binding | IPI | molecular_function |
| GO:0046683 | response to organophosphorus | IEP | biological_process |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0019966 | interleukin-1 binding | IPI | molecular_function |
| GO:0048386 | positive regulation of retinoic acid receptor sign | IDA | biological_process |
| GO:0045618 | positive regulation of keratinocyte differentiatio | IDA | biological_process |
| GO:0043966 | histone H3 acetylation | IDA | biological_process |
| GO:0060416 | response to growth hormone stimulus | IDA | biological_process |
| GO:0050718 | positive regulation of interleukin-1 beta secretio | IMP | biological_process |
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0045893 | positive regulation of transcription, DNA-dependen | IDA | biological_process |
| GO:0032526 | response to retinoic acid | IEP | biological_process |
| GO:0008270 | zinc ion binding | IEA | molecular_function |
| GO:0043967 | histone H4 acetylation | IDA | biological_process |
| GO:0005622 | intracellular | IEA | cellular_component |