| UniProt/SwissProt ID: | TR10C_HUMAN |
| Description: | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain [Source:HGNC Symbol;Acc:11906] |
| Location: | chr8 p21.3 |
| Node attribute: | PPI(target); receptor; gene |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S100 | QKHKSsCTMTR | TNFR_c6 | PhosphoSitePlus |
| S99 | DQKHKsSCTMT | TNFR_c6 | PhosphoSitePlus |
| Dephosphorylation site |
| TR10C_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000349324 | V246I | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000349324 | A78T | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| TR10C_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| TR10C_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| TNF10_HUMAN | TR10C_HUMAN | ligand -> receptor | HPMR |
| TNF10_HUMAN | TR10C_HUMAN | other | KEGG |
| P53_HUMAN | TR10C_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04650 | Natural killer cell mediated cytotoxicity |
| hsa04060 | Cytokine-cytokine receptor interaction |
| hsa05164 | Influenza A |
| hsa05162 | Measles |
| hsa04210 | Apoptosis |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0004888 | transmembrane signaling receptor activity | TAS | molecular_function |
| GO:0007165 | signal transduction | TAS | biological_process |
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0045569 | TRAIL binding | IEA | molecular_function |
| GO:0031225 | anchored to membrane | IEA | cellular_component |
| GO:0006915 | apoptotic process | IEA | biological_process |