Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TNR1B_HUMAN
Description:tumor necrosis factor receptor superfamily, member 1B [Source:HGNC Symbol;Acc:11917]
Location:chr1 p36.22
Node attribute:PPI(source); receptor; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S221LPQPVsTRSQHHPRD; SysPTM
T436RSQLEtPETLLPhosphoSitePlus; HPRD; phosphoELM
S221LPQPVsTRSQHDUF1191PhosphoSitePlus; SysPTM

Dephosphorylation site
TNR1B_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000365435T222PCOSMICCentral Nervous System Neoplasms18772890
ENSP00000365435V385LCOSMICHepatocellular Carcinoma
ENSP00000365435T222PTCGANeoplasms by Histologic Type21720365, 18772890

Differential expressed protein
TNR1B_HUMAN is not differential expressed protein.

Hyperphosphorylation site
TNR1B_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
TNFA_HUMANTNR1B_HUMANligand -> receptorHPMR
TNFB_HUMANTNR1B_HUMANotherKEGG
TNR1B_HUMANTRAF2_HUMANotherKEGG
TNFA_HUMANTNR1B_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04060Cytokine-cytokine receptor interaction
hsa04920Adipocytokine signaling pathway
hsa05014Amyotrophic lateral sclerosis (ALS)

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0008219cell deathIEAbiological_process
GO:0006915apoptotic processIEAbiological_process
GO:0006954inflammatory responseIEAbiological_process
GO:0016020membraneIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0045121membrane raftIDAcellular_component
GO:0043196varicosityIEAcellular_component
GO:0032496response to lipopolysaccharideIEAbiological_process
GO:0043025neuronal cell bodyIEAcellular_component
GO:0071363cellular response to growth factor stimulusIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0051044positive regulation of membrane protein ectodomainIMPbiological_process
GO:0030424axonIEAcellular_component
GO:0071222cellular response to lipopolysaccharideIMPbiological_process
GO:0050779RNA destabilizationIEAbiological_process
GO:0007166cell surface receptor signaling pathwayIEAbiological_process
GO:0005031tumor necrosis factor-activated receptor activityIEAmolecular_function
GO:0031625ubiquitin protein ligase bindingIPImolecular_function
GO:0048471perinuclear region of cytoplasmIEAcellular_component
GO:0033209tumor necrosis factor-mediated signaling pathwayIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0045121membrane raftIEAcellular_component
GO:0005886plasma membraneIEAcellular_component
GO:0006955immune responseIEAbiological_process
GO:0050728negative regulation of inflammatory responseIEAbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0005576extracellular regionIEAcellular_component


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