Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TIPIN_HUMAN
Description:TIMELESS interacting protein [Source:HGNC Symbol;Acc:30750]
Location:chr15 q22.31
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y15IDLPDyEHVEDPhosphoSitePlus
T293QQLDAtSRNITPhosphoSitePlus
T244VEEVNtDEDQKPhosphoSitePlus; HPRD
S222KLLSNsQTLGNPhosphoSitePlus; HPRD; phosphoELM
S192FASELsRSLTEPhosphoSitePlus
S282TLLDQsFKNVQPhosphoSitePlus
S194SELSRsLTEEQPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S220QAKLLsNSQTLPhosphoSitePlus; HPRD
T233DMLMNtPRAHTPhosphoSitePlus

Dephosphorylation site
TIPIN_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000261881M107ICOSMICOvarian Cancer21720365

Differential expressed protein
TIPIN_HUMAN is not differential expressed protein.

Hyperphosphorylation site
TIPIN_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ANPRB_HUMANTIPIN_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
TIPIN_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005794Golgi apparatusIDAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0007067mitosisIEAbiological_process
GO:0005634nucleusIDAcellular_component
GO:0033262regulation of DNA replication involved in S phaseTASbiological_process
GO:0009411response to UVIEAbiological_process
GO:0000076DNA replication checkpointIMPbiological_process
GO:0048478replication fork protectionIEAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0008284positive regulation of cell proliferationIMPbiological_process
GO:0000077DNA damage checkpointIEAbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0006974response to DNA damage stimulusIEAbiological_process
GO:0043231intracellular membrane-bounded organelleIDAcellular_component
GO:0031573intra-S DNA damage checkpointIMPbiological_process
GO:0033261regulation of S phaseIMPbiological_process
GO:0000790nuclear chromatinIDAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0007049cell cycleIEAbiological_process
GO:0051301cell divisionIEAbiological_process


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