| UniProt/SwissProt ID: | TIPIN_HUMAN |
| Description: | TIMELESS interacting protein [Source:HGNC Symbol;Acc:30750] |
| Location: | chr15 q22.31 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y15 | IDLPDyEHVED | PhosphoSitePlus | |
| T293 | QQLDAtSRNIT | PhosphoSitePlus | |
| T244 | VEEVNtDEDQK | PhosphoSitePlus; HPRD | |
| S222 | KLLSNsQTLGN | PhosphoSitePlus; HPRD; phosphoELM | |
| S192 | FASELsRSLTE | PhosphoSitePlus | |
| S282 | TLLDQsFKNVQ | PhosphoSitePlus | |
| S194 | SELSRsLTEEQ | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| S220 | QAKLLsNSQTL | PhosphoSitePlus; HPRD | |
| T233 | DMLMNtPRAHT | PhosphoSitePlus | |
| Dephosphorylation site |
| TIPIN_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000261881 | M107I | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| TIPIN_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| TIPIN_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ANPRB_HUMAN | TIPIN_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| TIPIN_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0007067 | mitosis | IEA | biological_process |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0033262 | regulation of DNA replication involved in S phase | TAS | biological_process |
| GO:0009411 | response to UV | IEA | biological_process |
| GO:0000076 | DNA replication checkpoint | IMP | biological_process |
| GO:0048478 | replication fork protection | IEA | biological_process |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0008284 | positive regulation of cell proliferation | IMP | biological_process |
| GO:0000077 | DNA damage checkpoint | IEA | biological_process |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0006974 | response to DNA damage stimulus | IEA | biological_process |
| GO:0043231 | intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0031573 | intra-S DNA damage checkpoint | IMP | biological_process |
| GO:0033261 | regulation of S phase | IMP | biological_process |
| GO:0000790 | nuclear chromatin | IDA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0007049 | cell cycle | IEA | biological_process |
| GO:0051301 | cell division | IEA | biological_process |