Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TIM23_HUMAN
Description:translocase of inner mitochondrial membrane 23 homolog (yeast) [Source:HGNC Symbol;Acc:17312]
Location:chr10 q11.23
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y168MTGMLyKCTGGPhosphoSitePlus
T164AAGTMtGMLYKPhosphoSitePlus

Dephosphorylation site
TIM23_HUMAN do not have dephosphorylation site.

Mutation site
TIM23_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000260867Testicular CancerNormal vs. Cancercell lineDown18489135

Hyperphosphorylation site
TIM23_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
RAF1_HUMANTIM23_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
TIM23_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0031305integral to mitochondrial inner membraneIDAcellular_component
GO:0005744mitochondrial inner membrane presequence translocaIDAcellular_component
GO:0005739mitochondrionIDAcellular_component
GO:0044267cellular protein metabolic processTASbiological_process
GO:0006886intracellular protein transportIEAbiological_process
GO:0005758mitochondrial intermembrane spaceIDAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0015450P-P-bond-hydrolysis-driven protein transmembrane tIEAmolecular_function
GO:0005743mitochondrial inner membraneTAScellular_component
GO:0006626protein targeting to mitochondrionTASbiological_process


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