| UniProt/SwissProt ID: | TIM23_HUMAN |
| Description: | translocase of inner mitochondrial membrane 23 homolog (yeast) [Source:HGNC Symbol;Acc:17312] |
| Location: | chr10 q11.23 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y168 | MTGMLyKCTGG | PhosphoSitePlus | |
| T164 | AAGTMtGMLYK | PhosphoSitePlus | |
| Dephosphorylation site |
| TIM23_HUMAN do not have dephosphorylation site. |
| Mutation site |
| TIM23_HUMAN do not have mutation site. |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000260867 | Testicular Cancer | Normal vs. Cancer | cell line | Down | 18489135 | |
| Hyperphosphorylation site |
| TIM23_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| RAF1_HUMAN | TIM23_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| TIM23_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0031305 | integral to mitochondrial inner membrane | IDA | cellular_component |
| GO:0005744 | mitochondrial inner membrane presequence transloca | IDA | cellular_component |
| GO:0005739 | mitochondrion | IDA | cellular_component |
| GO:0044267 | cellular protein metabolic process | TAS | biological_process |
| GO:0006886 | intracellular protein transport | IEA | biological_process |
| GO:0005758 | mitochondrial intermembrane space | IDA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane t | IEA | molecular_function |
| GO:0005743 | mitochondrial inner membrane | TAS | cellular_component |
| GO:0006626 | protein targeting to mitochondrion | TAS | biological_process |