Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TFAM_HUMAN
Description:transcription factor A, mitochondrial [Source:HGNC Symbol;Acc:11741]
Location:chr10 q21.1
Node attribute:substrate; gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S55PKKPVsSYLRFHPRD
T122FKEQLtPSQIMPhosphoSitePlus
S56KKPVSsYLRFSHPRD
S55PKKPVsSYLRFHMG_boxPhosphoSitePlus
S193NWKNLsDSEKEHMG_boxPhosphoSitePlus
S128PSQIMsLEKEIPhosphoSitePlus
S124EQLTPsQIMSLPhosphoSitePlus
S193NWKNLsDSEKEHPRD; phosphoELM
S195KNLSDsEKELYHMG_boxPhosphoSitePlus

Dephosphorylation site
TFAM_HUMAN do not have dephosphorylation site.

Mutation site
TFAM_HUMAN do not have mutation site.

Differential expressed protein
TFAM_HUMAN is not differential expressed protein.

Hyperphosphorylation site
TFAM_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KC1D_HUMANTFAM_HUMANkinase -> substrateRobert H Newman (2013)
KC1E_HUMANTFAM_HUMANkinase -> substrateRobert H Newman (2013)
STK24_HUMANTFAM_HUMANkinase -> substrateRobert H Newman (2013)
GABPA_HUMANTFAM_HUMANTF -> target geneTRANSFAC
NRF1_HUMANTFAM_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
TFAM_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0070363mitochondrial light strand promoter sense bindingIDAmolecular_function
GO:0031072heat shock protein bindingIEAmolecular_function
GO:0006356regulation of transcription from RNA polymerase I TASbiological_process
GO:0006391transcription initiation from mitochondrial promotIDAbiological_process
GO:0042645mitochondrial nucleoidIDAcellular_component
GO:0005739mitochondrionIEAcellular_component
GO:0005739mitochondrionIDAcellular_component
GO:0006390transcription from mitochondrial promoterIMPbiological_process
GO:0033108mitochondrial respiratory chain complex assemblyIEAbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIDAbiological_process
GO:0005759mitochondrial matrixTAScellular_component
GO:0006261DNA-dependent DNA replicationTASbiological_process
GO:0003700sequence-specific DNA binding transcription factorIMPmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0010467gene expressionTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0008301DNA binding, bendingIDAmolecular_function
GO:0003682chromatin bindingIDAmolecular_function


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