Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TF2AY_HUMAN
Description:general transcription factor IIA, 1-like [Source:HGNC Symbol;Acc:30727]
Location:chr2 p16.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S357SGDTSsNEEIGCK2a2RegPhos
S418EDPLNsGDDVSCK2a1RegPhos
S356GSGDTsSNEEICK2a2RegPhos
S356GSGDTsSNEEICK2a1RegPhos
S356GSGDTsSNEEICSNK2A1HPRD
S356GSGDTsSNEEICK2a1-rsRegPhos
S423SGDDVsEQDVPCSNK2A1HPRD
S423SGDDVsEQDVPCK2a2RegPhos
S423SGDDVsEQDVPCK2a1RegPhos
S418EDPLNsGDDVSCK2a2RegPhos
S357SGDTSsNEEIGCK2a1RegPhos
S418EDPLNsGDDVSCK2_groupphosphoELM; RegPhos
S356GSGDTsSNEEICK2_groupphosphoELM; RegPhos
S423SGDDVsEQDVPCSNK2A2HPRD
S418EDPLNsGDDVSCK2a1-rsRegPhos
S423SGDDVsEQDVPCK2a1-rsRegPhos
S357SGDTSsNEEIGCK2a1-rsRegPhos
S356GSGDTsSNEEICSNK2A2HPRD
S357SGDTSsNEEIGCSNK2A1HPRD
S357SGDTSsNEEIGCSNK2A2HPRD
S418EDPLNsGDDVSCSNK2A1HPRD
S418EDPLNsGDDVSCSNK2A2HPRD
S423SGDDVsEQDVPCK2_groupphosphoELM; RegPhos
S357SGDTSsNEEIGCK2_groupphosphoELM; RegPhos

Dephosphorylation site
TF2AY_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000384597D389GBIOMARTBreast Cancer21930507, 21930502
ENSP00000387896D355GBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
TF2AY_HUMAN is not differential expressed protein.

Hyperphosphorylation site
TF2AY_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CSK22_HUMANTF2AY_HUMANkinase -> substrateHPRD
CSK21_HUMANTF2AY_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05203Viral carcinogenesis
hsa03022Basal transcription factors

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005672transcription factor TFIIA complexIEAcellular_component
GO:0006366transcription from RNA polymerase II promoterTASbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0003713transcription coactivator activityTASmolecular_function
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0006367transcription initiation from RNA polymerase II prIEAbiological_process


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