Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TF2AA_HUMAN
Description:general transcription factor IIA, 1, 19/37kDa [Source:HGNC Symbol;Acc:4646]
Location:chr14 q31.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S316EEPLNsEDDVSCK2a2RegPhos
S316EEPLNsEDDVSTAF1HPRD; RegPhos
S316EEPLNsEDDVSTFIIA; SyndecanPhosphoSitePlus
S280GTGDTsSEEDETAF1HPRD; RegPhos
S277EEPLNsEDDVSTAF1HPRD
S321SEDDVsDEEGQCK2a1RegPhos
S321SEDDVsDEEGQCK2a2RegPhos
S321SEDDVsDEEGQCK2a1-rsRegPhos
S321SEDDVsDEEGQCK2_groupphosphoELM; RegPhos
S281TGDTSsEEDEDTFIIA; SyndecanPhosphoSitePlus
S241GTGDTsSEEDECSNK2A2HPRD
S241GTGDTsSEEDECSNK2A1HPRD
S316EEPLNsEDDVSCK2_groupphosphoELM; RegPhos
S321SEDDVsDEEGQTFIIA; SyndecanPhosphoSitePlus
S281TGDTSsEEDEDCK2a2RegPhos
S280GTGDTsSEEDECK2a2RegPhos
S280GTGDTsSEEDECK2a1RegPhos
S277EEPLNsEDDVSCSNK2A1HPRD
S277EEPLNsEDDVSCSNK2A2HPRD
S316EEPLNsEDDVSCK2a1RegPhos
S281TGDTSsEEDEDCK2a1-rsRegPhos
S241GTGDTsSEEDETAF1HPRD
T9SANTNtVPKLYPhosphoSitePlus
S242TGDTSsEEDEDCSNK2A2HPRD
S281TGDTSsEEDEDCSNK2A1HPRD
S281TGDTSsEEDEDCSNK2A2HPRD
S282SEDDVsDEEGQCSNK2A1HPRD
S282SEDDVsDEEGQCSNK2A2HPRD
S316EEPLNsEDDVSCSNK2A2HPRD
S316EEPLNsEDDVSCSNK2A1HPRD
S321SEDDVsDEEGQTAF1HPRD; RegPhos
S321SEDDVsDEEGQCSNK2A1HPRD
S280GTGDTsSEEDETFIIA; SyndecanPhosphoSitePlus
S281TGDTSsEEDEDTAF1HPRD; RegPhos
S242TGDTSsEEDEDCSNK2A1HPRD
S282SEDDVsDEEGQTAF1HPRD
S280GTGDTsSEEDECK2_groupphosphoELM; RegPhos
S280GTGDTsSEEDECSNK2A2HPRD
S280GTGDTsSEEDECSNK2A1HPRD
S281TGDTSsEEDEDCK2a1RegPhos
S242TGDTSsEEDEDTAF1HPRD
S280GTGDTsSEEDECK2a1-rsRegPhos
S281TGDTSsEEDEDCK2_groupphosphoELM; RegPhos
S316EEPLNsEDDVSCK2a1-rsRegPhos
S321SEDDVsDEEGQCSNK2A2HPRD

Dephosphorylation site
TF2AA_HUMAN do not have dephosphorylation site.

Mutation site
TF2AA_HUMAN do not have mutation site.

Differential expressed protein
TF2AA_HUMAN is not differential expressed protein.

Hyperphosphorylation site
TF2AA_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CSK21_HUMANTF2AA_HUMANkinase -> substrateHPRD
CSK22_HUMANTF2AA_HUMANkinase -> substrateHPRD
TAF1_HUMANTF2AA_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa03022Basal transcription factors
hsa05203Viral carcinogenesis

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006366transcription from RNA polymerase II promoterIDAbiological_process
GO:0006367transcription initiation from RNA polymerase II prTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0005654nucleoplasmTAScellular_component
GO:0046982protein heterodimerization activityIPImolecular_function
GO:0003713transcription coactivator activityTASmolecular_function
GO:0005672transcription factor TFIIA complexIDAcellular_component
GO:0008134transcription factor bindingIPImolecular_function
GO:0003677DNA bindingIDAmolecular_function
GO:0010467gene expressionTASbiological_process
GO:0017025TBP-class protein bindingIPImolecular_function
GO:0016032viral reproductionTASbiological_process
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0006368transcription elongation from RNA polymerase II prTASbiological_process


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