| UniProt/SwissProt ID: | TBL2_HUMAN |
| Description: | transducin (beta)-like 2 [Source:HGNC Symbol;Acc:11586] |
| Location: | chr7 q11.23 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T433 | LQQQLtQAQET | ATR | RegPhos |
| Y174 | REDGGyTFTAT | PhosphoSitePlus | |
| Y104 | SSNGKyLATCA | HPRD | |
| T433 | LQQQLtQAQET | PhosphoSitePlus; HPRD; phosphoELM | |
| T433 | LQQQLtQAQET | ATM | RegPhos |
| Dephosphorylation site |
| TBL2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000307260 | E366Q | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000307260 | V14L | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| TBL2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| TBL2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ATR_HUMAN | TBL2_HUMAN | kinase -> substrate | RegPhos |
| ATM_HUMAN | TBL2_HUMAN | kinase -> substrate | RegPhos |
| Function Annotation |
| KEGG Pathway |
| TBL2_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005575 | cellular_component | ND | cellular_component |
| GO:0008150 | biological_process | ND | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0003674 | molecular_function | ND | molecular_function |