Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TAGL_HUMAN
Description:transgelin [Source:HGNC Symbol;Acc:11553]
Location:chr11 q23.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y145KNDGHyRGDPNPhosphoSitePlus
S181GLQMGsNRGASPKC_groupphosphoELM; RegPhos; SysPTM
T191SQAGMtGYGRPCalponinPhosphoSitePlus
S181GLQMGsNRGASPRKCDHPRD; SysPTM
Y22KIEKKyDEELEPhosphoSitePlus
S11PSYGMsREVQSPhosphoSitePlus
Y193AGMTGyGRPRQHPRD; phosphoELM
S181GLQMGsNRGASCalponinPhosphoSitePlus; SysPTM
S181GLQMGsNRGASPKCdRegPhos; SysPTM
S186SNRGAsQAGMTCalponinPhosphoSitePlus
S166REFTEsQLQEGPhosphoSitePlus
S63NGVILsKLVNSCHPhosphoSitePlus
Y193AGMTGyGRPRQCalponinPhosphoSitePlus
S68SKLVNsLYPDGCHPhosphoSitePlus
S135LMALGsLAVTKCHPhosphoSitePlus
T139GSLAVtKNDGHPhosphoSitePlus; HPRD
Y70LVNSLyPDGSKCHPhosphoSitePlus
Y104KAAEDyGVIKTCHPhosphoSitePlus
T164HKREFtESQLQPhosphoSitePlus; HPRD; SysPTM

Dephosphorylation site
TAGL_HUMAN do not have dephosphorylation site.

Mutation site
TAGL_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000278968colorectal cancerNormal vs. CancertissueUp4.119098285
ENSP00000278968colorectal cancerNormal vs. CancertissueDown0.6914997500
ENSP00000278968colorectal cancerNormal vs. CancertissueDown0.8914997500
ENSP00000278968colorectal cancerNormal vs. CancertissueUp1.114997500
ENSP00000278968Gastric CancerNormal vs. CancertissueUp3.217929853
ENSP00000278968Breast CancerNormal vs. CancertissueUp>1020005186
ENSP00000278968Breast CancerNormal vs. CancertissueDown0.5720739354
ENSP00000278968Breast CancerNormal vs. CancertissueDown0.5720739354
ENSP00000278968Oral CancerNormal vs. CancertissueUp3.319691830
ENSP00000278968Ovarian CancerMetastasiscell lineDown0.217892554
ENSP00000278968pancreatic ductal adenocarcinomaNormal vs. CancertissueDown0.2215924292
ENSP00000278968Gastric CancerNormal vs. Cancercell lineDown0.0820812763
ENSP00000278968Gastric CancerNormal vs. Cancercell lineDown0.0220812763
ENSP00000278968pancreatic ductal adenocarcinomaNormal vs. CancertissueUp17492507

Hyperphosphorylation site
TAGL_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KPCD_HUMANTAGL_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
TAGL_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005737cytoplasmIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0003779actin bindingIEAmolecular_function
GO:0007517muscle organ developmentIEAbiological_process


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