| UniProt/SwissProt ID: | TAGL_HUMAN |
| Description: | transgelin [Source:HGNC Symbol;Acc:11553] |
| Location: | chr11 q23.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y145 | KNDGHyRGDPN | PhosphoSitePlus | |
| S181 | GLQMGsNRGAS | PKC_group | phosphoELM; RegPhos; SysPTM |
| T191 | SQAGMtGYGRP | Calponin | PhosphoSitePlus |
| S181 | GLQMGsNRGAS | PRKCD | HPRD; SysPTM |
| Y22 | KIEKKyDEELE | PhosphoSitePlus | |
| S11 | PSYGMsREVQS | PhosphoSitePlus | |
| Y193 | AGMTGyGRPRQ | HPRD; phosphoELM | |
| S181 | GLQMGsNRGAS | Calponin | PhosphoSitePlus; SysPTM |
| S181 | GLQMGsNRGAS | PKCd | RegPhos; SysPTM |
| S186 | SNRGAsQAGMT | Calponin | PhosphoSitePlus |
| S166 | REFTEsQLQEG | PhosphoSitePlus | |
| S63 | NGVILsKLVNS | CH | PhosphoSitePlus |
| Y193 | AGMTGyGRPRQ | Calponin | PhosphoSitePlus |
| S68 | SKLVNsLYPDG | CH | PhosphoSitePlus |
| S135 | LMALGsLAVTK | CH | PhosphoSitePlus |
| T139 | GSLAVtKNDGH | PhosphoSitePlus; HPRD | |
| Y70 | LVNSLyPDGSK | CH | PhosphoSitePlus |
| Y104 | KAAEDyGVIKT | CH | PhosphoSitePlus |
| T164 | HKREFtESQLQ | PhosphoSitePlus; HPRD; SysPTM | |
| Dephosphorylation site |
| TAGL_HUMAN do not have dephosphorylation site. |
| Mutation site |
| TAGL_HUMAN do not have mutation site. |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000278968 | colorectal cancer | Normal vs. Cancer | tissue | Up | 4.1 | 19098285 | ENSP00000278968 | colorectal cancer | Normal vs. Cancer | tissue | Down | 0.69 | 14997500 | ENSP00000278968 | colorectal cancer | Normal vs. Cancer | tissue | Down | 0.89 | 14997500 | ENSP00000278968 | colorectal cancer | Normal vs. Cancer | tissue | Up | 1.1 | 14997500 | ENSP00000278968 | Gastric Cancer | Normal vs. Cancer | tissue | Up | 3.2 | 17929853 | ENSP00000278968 | Breast Cancer | Normal vs. Cancer | tissue | Up | >10 | 20005186 | ENSP00000278968 | Breast Cancer | Normal vs. Cancer | tissue | Down | 0.57 | 20739354 | ENSP00000278968 | Breast Cancer | Normal vs. Cancer | tissue | Down | 0.57 | 20739354 | ENSP00000278968 | Oral Cancer | Normal vs. Cancer | tissue | Up | 3.3 | 19691830 | ENSP00000278968 | Ovarian Cancer | Metastasis | cell line | Down | 0.2 | 17892554 | ENSP00000278968 | pancreatic ductal adenocarcinoma | Normal vs. Cancer | tissue | Down | 0.22 | 15924292 | ENSP00000278968 | Gastric Cancer | Normal vs. Cancer | cell line | Down | 0.08 | 20812763 | ENSP00000278968 | Gastric Cancer | Normal vs. Cancer | cell line | Down | 0.02 | 20812763 | ENSP00000278968 | pancreatic ductal adenocarcinoma | Normal vs. Cancer | tissue | Up | 17492507 |
| Hyperphosphorylation site |
| TAGL_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KPCD_HUMAN | TAGL_HUMAN | kinase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| TAGL_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0003779 | actin binding | IEA | molecular_function |
| GO:0007517 | muscle organ development | IEA | biological_process |