Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TAB2_HUMAN
Description:TGF-beta activated kinase 1/MAP3K7 binding protein 2 [Source:HGNC Symbol;Acc:17075]
Location:chr6 q25.1
Node attribute:PPI(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S588ISQIPsLEEMQIncAPhosphoSitePlus
S527KLSMGsDDAAYHPRD
S440HHPPKsRAIGNPhosphoSitePlus
T456PRVVVtQPNTKPhosphoSitePlus
S482SPGVVsPTFELHPRD; phosphoELM
S419GASAAsRNMSGPhosphoSitePlus
S477KPPAVsPGVVSHPRD; phosphoELM
T484GVVSPtFELTNHPRD
S447AIGNNsATSPRPhosphoSitePlus
T449GNNSAtSPRVVHPRD
S524ETRKLsMGSDDIncAPhosphoSitePlus
S527KLSMGsDDAAYIncAPhosphoSitePlus
S423ASRNMsGQVSMPhosphoSitePlus
S450NNSATsPRVVVPhosphoSitePlus; HPRD
S524ETRKLsMGSDDHPRD
T171SLSQQtPRFNPPhosphoSitePlus
Y632AIHNFyDNIGFPhosphoSitePlus
Y532SDDAAyTQALLHPRD; phosphoELM
S372VYIAAsPPNTDPhosphoSitePlus; HPRD; phosphoELM
S350GPRTSsTSSSVPhosphoSitePlus
S413FISTNsGASAAPhosphoSitePlus
S582LKRSNsISQIPDivIC; IncAPhosphoSitePlus
T510HLTDPtLAHVDHPRD

Dephosphorylation site
TAB2_HUMAN do not have dephosphorylation site.

Mutation site
TAB2_HUMAN do not have mutation site.

Differential expressed protein
TAB2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
TAB2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
TAB2_HUMANM3K7_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05140Leishmaniasis
hsa05168Herpes simplex infection
hsa04380Osteoclast differentiation
hsa04620Toll-like receptor signaling pathway
hsa04010MAPK signaling pathway
hsa05162Measles
hsa05145Toxoplasmosis
hsa04621NOD-like receptor signaling pathway
hsa05169Epstein-Barr virus infection
hsa04064NF-kappa B signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0045087innate immune responseTASbiological_process
GO:0035872nucleotide-binding domain, leucine rich repeat conTASbiological_process
GO:0034142toll-like receptor 4 signaling pathwayTASbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0002756MyD88-independent toll-like receptor signaling patTASbiological_process
GO:0045860positive regulation of protein kinase activityIDAbiological_process
GO:0034138toll-like receptor 3 signaling pathwayTASbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0008063Toll signaling pathwayTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0050852T cell receptor signaling pathwayTASbiological_process
GO:0051403stress-activated MAPK cascadeTASbiological_process
GO:0005829cytosolTAScellular_component
GO:0070423nucleotide-binding oligomerization domain containiTASbiological_process
GO:0002755MyD88-dependent toll-like receptor signaling pathwTASbiological_process
GO:0034134toll-like receptor 2 signaling pathwayTASbiological_process
GO:0005622intracellularIEAcellular_component
GO:0008270zinc ion bindingIEAmolecular_function
GO:0007507heart developmentIMPbiological_process
GO:0002224toll-like receptor signaling pathwayTASbiological_process
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cIEPbiological_process
GO:0007249I-kappaB kinase/NF-kappaB cascadeTASbiological_process
GO:0070530K63-linked polyubiquitin bindingIDAmolecular_function
GO:0007254JNK cascadeTASbiological_process
GO:0035666TRIF-dependent toll-like receptor signaling pathwaTASbiological_process
GO:0000187activation of MAPK activityTASbiological_process
GO:0010008endosome membraneTAScellular_component
GO:0051092positive regulation of NF-kappaB transcription facTASbiological_process
GO:0034130toll-like receptor 1 signaling pathwayTASbiological_process


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