| UniProt/SwissProt ID: | SYN3_HUMAN |
| Description: | synapsin III [Source:HGNC Symbol;Acc:11496] |
| Location: | chr22 q12.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S552 | STSDTsQRGTP | PhosphoSitePlus | |
| S455 | PQRSGsPSQQR | PhosphoSitePlus | |
| S473 | PLSPQsGSPQQ | PhosphoSitePlus | |
| S470 | GQQPLsPQSGS | MAPK3 | phosphoELM |
| S453 | PQPQRsGSPSQ | PhosphoSitePlus | |
| S470 | GQQPLsPQSGS | CDC2(CDK1 | RegPhos |
| S470 | GQQPLsPQSGS | PhosphoSitePlus; HPRD; RegPhos | |
| S470 | GQQPLsPQSGS | Erk1(MAPK3 | RegPhos |
| S484 | QRSPGsPQLSR | PhosphoSitePlus; RegPhos | |
| S475 | SPQSGsPQQQR | PhosphoSitePlus | |
| S457 | RSGSPsQQRLS | PhosphoSitePlus | |
| S470 | GQQPLsPQSGS | CDK1 | phosphoELM |
| T32 | RPDSStSSPAS | Synapsin_N | PhosphoSitePlus |
| S462 | SQQRLsPQGQQ | PhosphoSitePlus; RegPhos | |
| Dephosphorylation site |
| SYN3_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000351614 | V246L | COSMIC | Melanoma | 21499247 | ENSP00000351614 | S447C | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000351614 | A66T | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000351614 | S462F | COSMIC | Skin Cancer | 21984974 |
| Differential expressed protein |
| SYN3_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| SYN3_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| MK03_HUMAN | SYN3_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| CDK1_HUMAN | SYN3_HUMAN | kinase -> substrate | RegPhos |
| ZAGL2_HUMAN | SYN3_HUMAN | kinase -> substrate | RegPhos |
| Function Annotation |
| KEGG Pathway |
| SYN3_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0030054 | cell junction | IEA | cellular_component |
| GO:0007269 | neurotransmitter secretion | IEA | biological_process |
| GO:0008021 | synaptic vesicle | IEA | cellular_component |
| GO:0030672 | synaptic vesicle membrane | IEA | cellular_component |
| GO:0045202 | synapse | IEA | cellular_component |
| GO:0008021 | synaptic vesicle | TAS | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0003824 | catalytic activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |