Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SUMO3_HUMAN
Description:SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae) [Source:HGNC Symbol;Acc:11124]
Location:chr21 q22.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S53ERQGLsMRQIRubiquitinPhosphoSitePlus
T37KIKRHtPLSKLubiquitinPhosphoSitePlus
S27AGQDGsVVQFKubiquitinPhosphoSitePlus

Dephosphorylation site
SUMO3_HUMAN do not have dephosphorylation site.

Mutation site
SUMO3_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000330343Breast CancerNormal vs. CancertissueUp17127214
ENSP00000330343Breast CancerNormal vs. CancertissueUp17004105
ENSP00000330343Breast CancerNormal vs. Cancercell lineDown0.3820052998
ENSP00000330343Breast CancerNormal vs. Cancercell lineDown0.5520052998
ENSP00000330343Breast CancerMetastasiscell lineUp1.520052998

Hyperphosphorylation site
SUMO3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
MK08_HUMANSUMO3_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
SUMO3_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:2000060positive regulation of protein ubiquitination invoIEAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0016604nuclear bodyIEAcellular_component
GO:0034504protein localization to nucleusIEAbiological_process
GO:0019789SUMO ligase activityIEAmolecular_function
GO:0016925protein sumoylationIDAbiological_process
GO:0000776kinetochoreTAScellular_component


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