| UniProt/SwissProt ID: | SUMO3_HUMAN |
| Description: | SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae) [Source:HGNC Symbol;Acc:11124] |
| Location: | chr21 q22.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S53 | ERQGLsMRQIR | ubiquitin | PhosphoSitePlus |
| T37 | KIKRHtPLSKL | ubiquitin | PhosphoSitePlus |
| S27 | AGQDGsVVQFK | ubiquitin | PhosphoSitePlus |
| Dephosphorylation site |
| SUMO3_HUMAN do not have dephosphorylation site. |
| Mutation site |
| SUMO3_HUMAN do not have mutation site. |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000330343 | Breast Cancer | Normal vs. Cancer | tissue | Up | 17127214 | ENSP00000330343 | Breast Cancer | Normal vs. Cancer | tissue | Up | 17004105 | ENSP00000330343 | Breast Cancer | Normal vs. Cancer | cell line | Down | 0.38 | 20052998 | ENSP00000330343 | Breast Cancer | Normal vs. Cancer | cell line | Down | 0.55 | 20052998 | ENSP00000330343 | Breast Cancer | Metastasis | cell line | Up | 1.5 | 20052998 |
| Hyperphosphorylation site |
| SUMO3_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| MK08_HUMAN | SUMO3_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| SUMO3_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:2000060 | positive regulation of protein ubiquitination invo | IEA | biological_process |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0016604 | nuclear body | IEA | cellular_component |
| GO:0034504 | protein localization to nucleus | IEA | biological_process |
| GO:0019789 | SUMO ligase activity | IEA | molecular_function |
| GO:0016925 | protein sumoylation | IDA | biological_process |
| GO:0000776 | kinetochore | TAS | cellular_component |