Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:STX1A_HUMAN
Description:syntaxin 1A (brain) [Source:HGNC Symbol;Acc:11433]
Location:chrHG1257_PATCH q11.
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S14RTAKDsDDDDDCK2_groupphosphoELM; RegPhos; SysPTM
S14RTAKDsDDDDDApoLp-III; MCPsignalPhosphoSitePlus; SysPTM
S64SAILAsPNPDEHPRD; SysPTM
S14RTAKDsDDDDDCK2a1-rsRegPhos; SysPTM
S64SAILAsPNPDEApoLp-III; Ferritin; DUF1PhosphoSitePlus; SysPTM
T282IVIAStVGGIFTM; T2SF; GNVRPhosphoSitePlus
S188MDSSIsKQALSDAPK_groupphosphoELM; RegPhos
S281GIVIAsTVGGITM; T2SF; GNVRPhosphoSitePlus
S14RTAKDsDDDDDCSNK2A1HPRD; SysPTM
S14RTAKDsDDDDDCSNK2A2HPRD; SysPTM
S14RTAKDsDDDDDCK2a2RegPhos; SysPTM
S249VERAVsDTKKAAAA_13; DUF966; Filo_VP35PhosphoSitePlus
S14RTAKDsDDDDDCK2a1RegPhos; SysPTM
S188MDSSIsKQALSDAPK1HPRD; RegPhos
S14RTAKDsDDDDDphosphoELM; RegPhos; SysPTM

Dephosphorylation site
STX1A_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000222812S59NCOSMICSkin Cancer21984974

Differential expressed protein
STX1A_HUMAN is not differential expressed protein.

Hyperphosphorylation site
STX1A_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CSK22_HUMANSTX1A_HUMANkinase -> substrateHPRD
DAPK1_HUMANSTX1A_HUMANkinase -> substrateHPRD; RegPhos
ZAGL2_HUMANSTX1A_HUMANkinase -> substrateRegPhos
CSK21_HUMANSTX1A_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05031Amphetamine addiction
hsa04721Synaptic vesicle cycle
hsa04130SNARE interactions in vesicular transport

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0019904protein domain specific bindingIEAmolecular_function
GO:0017022myosin bindingIEAmolecular_function
GO:0017157regulation of exocytosisIEAbiological_process
GO:0014047glutamate secretionTASbiological_process
GO:0044281small molecule metabolic processTASbiological_process
GO:0016192vesicle-mediated transportIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0045921positive regulation of exocytosisIEAbiological_process
GO:0047485protein N-terminus bindingIEAmolecular_function
GO:0005484SNAP receptor activityIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0006112energy reserve metabolic processTASbiological_process
GO:0006886intracellular protein transportIEAbiological_process
GO:0009629response to gravityIEAbiological_process
GO:0008021synaptic vesicleIEAcellular_component
GO:0001956positive regulation of neurotransmitter secretionIEAbiological_process
GO:0030141secretory granuleIEAcellular_component
GO:0030672synaptic vesicle membraneIEAcellular_component
GO:0000149SNARE bindingIEAmolecular_function
GO:0032028myosin head/neck bindingIEAmolecular_function
GO:0007268synaptic transmissionTASbiological_process
GO:0043229intracellular organelleIEAcellular_component
GO:0016020membraneIEAcellular_component
GO:0007269neurotransmitter secretionTASbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0019855calcium channel inhibitor activityIEAmolecular_function
GO:0043005neuron projectionIDAcellular_component
GO:0017156calcium ion-dependent exocytosisIEAbiological_process
GO:0043008ATP-dependent protein bindingIEAmolecular_function
GO:0005576extracellular regionIEAcellular_component
GO:0016081synaptic vesicle docking involved in exocytosisIEAbiological_process
GO:0050796regulation of insulin secretionTASbiological_process
GO:0030674protein binding, bridgingIEAmolecular_function
GO:0005886plasma membraneTAScellular_component
GO:0048306calcium-dependent protein bindingIEAmolecular_function
GO:0005886plasma membraneIEAcellular_component
GO:0070044synaptobrevin 2-SNAP-25-syntaxin-1a complexIEAcellular_component
GO:0001948glycoprotein bindingIEAmolecular_function
GO:0043234protein complexIEAcellular_component
GO:0070032synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I coIEAcellular_component
GO:0030054cell junctionIEAcellular_component
GO:0042641actomyosinIEAcellular_component
GO:0046982protein heterodimerization activityIEAmolecular_function
GO:0031201SNARE complexIDAcellular_component


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23