| UniProt/SwissProt ID: | STMN2_HUMAN |
| Description: | stathmin-like 2 [Source:HGNC Symbol;Acc:10577] |
| Location: | chr8 q21.13 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S73 | PRTLAsPKKKD | MAPK3 | HPRD |
| S73 | PRTLAsPKKKD | CDC2 | RegPhos |
| S97 | EERRKsQEAQV | PKACa | RegPhos |
| S62 | ILKPPsPISEA | Erk1 | RegPhos |
| S62 | ILKPPsPISEA | Stathmin | PhosphoSitePlus |
| S73 | PRTLAsPKKKD | CDK1 | HPRD |
| S97 | EERRKsQEAQV | RegPhos | |
| S62 | ILKPPsPISEA | MAPK3 | HPRD |
| S62 | ILKPPsPISEA | MAPK_group | phosphoELM; RegPhos |
| S50 | INKRAsGQAFE | RegPhos | |
| S73 | PRTLAsPKKKD | Erk1 | RegPhos |
| S80 | KKKDLsLEEIQ | HPRD; phosphoELM; RegPhos; SysPTM | |
| S73 | PRTLAsPKKKD | MAPK_group | phosphoELM; RegPhos |
| S80 | KKKDLsLEEIQ | Stathmin | PhosphoSitePlus; SysPTM |
| S97 | EERRKsQEAQV | PRKACA | HPRD |
| S50 | INKRAsGQAFE | PKACa | RegPhos |
| S16 | KMKELsMLSLI | RegPhos | |
| S62 | ILKPPsPISEA | RegPhos | |
| S73 | PRTLAsPKKKD | RegPhos | |
| S50 | INKRAsGQAFE | PRKACA | HPRD |
| Dephosphorylation site |
| STMN2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000220876 | A49T | COSMIC | Ovarian Cancer | 21720365 | ENSP00000220876 | R69Q | COSMIC | Skin Cancer | 21984974 |
| Differential expressed protein |
| STMN2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| STMN2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CDK1_HUMAN | STMN2_HUMAN | kinase -> substrate | HPRD; RegPhos |
| KPCA_HUMAN | STMN2_HUMAN | kinase -> substrate | HPRD |
| MK03_HUMAN | STMN2_HUMAN | kinase -> substrate | HPRD |
| ZAGL2_HUMAN | STMN2_HUMAN | kinase -> substrate | RegPhos |
| Function Annotation |
| KEGG Pathway |
| STMN2_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005768 | endosome | IEA | cellular_component |
| GO:0031115 | negative regulation of microtubule polymerization | IDA | biological_process |
| GO:0048471 | perinuclear region of cytoplasm | IDA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0031110 | regulation of microtubule polymerization or depoly | IEA | biological_process |
| GO:0030424 | axon | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0007026 | negative regulation of microtubule depolymerizatio | IDA | biological_process |
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0031982 | vesicle | IEA | cellular_component |
| GO:0010977 | negative regulation of neuron projection developme | IDA | biological_process |
| GO:0010976 | positive regulation of neuron projection developme | IDA | biological_process |
| GO:0030182 | neuron differentiation | NAS | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0031117 | positive regulation of microtubule depolymerizatio | IDA | biological_process |
| GO:0030426 | growth cone | IEA | cellular_component |