Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:STK39_HUMAN
Description:serine threonine kinase 39 [Source:HGNC Symbol;Acc:17717]
Location:chr2 q24.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T235KTFVGtPCWMAPkinasePhosphoSitePlus
T231NKVRKtFVGTPPkinasePhosphoSitePlus
S430QIQSLsVHDSQPhosphoSitePlus
S325LQKDPsKRPTAPKCt(PKC thetaRegPhos
T354KLLTRtPDIAQPhosphoSitePlus
S311KKYGKsFRKLLPKCtRegPhos
S370RRVPGsSGHLHPhosphoSitePlus; HPRD
Y276APYHKyPPMKVPkinasePhosphoSitePlus
S311KKYGKsFRKLLPKCt(PKC thetaRegPhos
S311KKYGKsFRKLLPKC_thetaphosphoELM
S385GDWEWsDDEMDPhosphoSitePlus; HPRD
S373RVPGSsGHLHKWNK1phosphoELM
T356KLLTRtPDIAQphosphoELM; RegPhos; SysPTM
S387GDWEWsDDEMDphosphoELM; RegPhos; SysPTM
Y273TGAAPyHKYPPPkinasePhosphoSitePlus
S309KKYGKsFRKLLPRKCQHPRD
S323LQKDPsKRPTAPRKCQHPRD
S372RRVPGsSGHLHphosphoELM; RegPhos; SysPTM
T233NKVRKtFVGTPWnk1RegPhos
S323LQKDPsKRPTAPkinasePhosphoSitePlus
Y63ICRDAyELQEVPkinasePhosphoSitePlus
Y444NANEDyREASSPhosphoSitePlus
S371RVPGSsGHLHKPhosphoSitePlus; HPRD
S373RVPGSsGHLHKWnk1RegPhos
S309KKYGKsFRKLLPkinasePhosphoSitePlus
S325LQKDPsKRPTAPKC_thetaphosphoELM
T219SAFLAtGGDVTPkinasePhosphoSitePlus
S325LQKDPsKRPTAPKCtRegPhos
T224TGGDVtRNKVRPkinasePhosphoSitePlus
T233NKVRKtFVGTPWNK1phosphoELM
Y306EMMKKyGKSFRPkinasePhosphoSitePlus
S373RVPGSsGHLHKphosphoELM
S448DYREAsSCAVNPhosphoSitePlus

Dephosphorylation site
STK39_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000348278L331FGreenman2007Skin Cancer17344846, 18428421
ENSP00000348278I208TBIOMARTNeoplasms by Histologic Type21930507, 21930502

Differential expressed protein
STK39_HUMAN is not differential expressed protein.

Hyperphosphorylation site
STK39_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
WNK1_HUMANSTK39_HUMANkinase -> substrateRobert H Newman (2013)
KPCT_HUMANSTK39_HUMANkinase -> substrateHPRD; NetPath; Robert H Newman (2013)
ZAGL2_HUMANSTK39_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
STK39_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0050727regulation of inflammatory responseIEAbiological_process
GO:0004672protein kinase activityIEAmolecular_function
GO:0005737cytoplasmIEAcellular_component
GO:0016324apical plasma membraneIEAcellular_component
GO:0004674protein serine/threonine kinase activityIEAmolecular_function
GO:0023014signal transduction by phosphorylationNASbiological_process
GO:0016323basolateral plasma membraneIEAcellular_component
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0043268positive regulation of potassium ion transportIEAbiological_process
GO:0019901protein kinase bindingIEAmolecular_function
GO:0006468protein phosphorylationIEAbiological_process
GO:0005524ATP bindingNASmolecular_function
GO:0005634nucleusNAScellular_component
GO:0006950response to stressNASbiological_process
GO:0004702receptor signaling protein serine/threonine kinaseNASmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0005856cytoskeletonIEAcellular_component
GO:0005737cytoplasmNAScellular_component
GO:0016020membraneIEAcellular_component
GO:0006468protein phosphorylationNASbiological_process


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