UniProt/SwissProt ID: | STK36_HUMAN |
Description: | serine/threonine kinase 36 [Source:HGNC Symbol;Acc:17209] |
Location: | chr2 q35 |
Node attribute: | kinase |
Phosphorylation site |
Position | PhosphoPeptide | Catalytic kinase | Source |
---|---|---|---|
Y1181 | VGNAAyQAGPL | PhosphoSitePlus | |
S159 | TMVLTsIKGTP | Pkinase | PhosphoSitePlus |
S578 | AQPDDsEQTLR | PhosphoSitePlus | |
S151 | FARAMsTNTMV | Pkinase | PhosphoSitePlus |
Y19 | SFGRVyKGRRK | Pkinase | PhosphoSitePlus |
T581 | DDSEQtLRRDS | PhosphoSitePlus | |
Dephosphorylation site |
STK36_HUMAN do not have dephosphorylation site. |
Mutation site |
Ensembl ID | Variation | Source | Cancer name | Pubmed |
---|---|---|---|---|
ENSP00000295709 | R1209P | Ding2008, BIOMART | Lung Cancer | 18948947, 21930507, 21930502 |
ENSP00000295709 | S767Y | Greenman2007, HPI | Ovarian Cancer | 17344846, 18428421 |
ENSP00000375954 | E878Q | BIOMART | Breast Cancer | 21930507, 21930502 |
ENSP00000295709 | L1147V | BIOMART | chronic lymphocytic leukemia | 21930507, 21930502 |
ENSP00000295709 | E899Q | BIOMART | Breast Cancer | 21930507, 21930502 |
ENSP00000295709 | Q1138K | Greenman2007, HPI | Ovarian Cancer | 17344846, 18428421 |
ENSP00000295709 | P1185S | Greenman2007 | Ovarian Cancer | 17344846, 18428421 |
ENSP00000295709 | S660C | Greenman2007, HPI | Breast Cancer | 15908952, 17344846, 18428421 |
ENSP00000394095 | S767Y | HPI | Ovarian Cancer | 17344846 |
ENSP00000394095 | S660C | HPI | Breast Cancer | 17344846 |
ENSP00000394095 | E899Q | BIOMART | Breast Cancer | 21930507, 21930502 |
ENSP00000295709 | G844V | Ding2008, BIOMART | Lung Cancer | 18948947, 21930507, 21930502 |
ENSP00000394095 | Q1138K | HPI | Ovarian Cancer | 17344846 |
Differential expressed protein |
STK36_HUMAN is not differential expressed protein. |
Hyperphosphorylation site |
STK36_HUMAN do not have hyperphosphorylation site. |
Direct Interaction Pair |
Source | Target | Relationship | Resource |
---|---|---|---|
STK36_HUMAN | NFAC4_HUMAN | kinase -> substrate | Robert H Newman (2013) |
STK36_HUMAN | NDF1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
STK36_HUMAN | CRY1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
STK36_HUMAN | BPL1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
STK36_HUMAN | UHMK1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
STK36_HUMAN | AIRE_HUMAN | kinase -> substrate | Robert H Newman (2013) |
Function Annotation |
KEGG Pathway |
STK36_HUMAN is not in KEGG pathway. |
Gene Ontology |
GO ID | GO_Term | Evidence | Ontology |
---|---|---|---|
GO:0004672 | protein kinase activity | IEA | molecular_function |
GO:0008134 | transcription factor binding | IDA | molecular_function |
GO:0003351 | epithelial cilium movement | IEA | biological_process |
GO:0006468 | protein phosphorylation | NAS | biological_process |
GO:0000287 | magnesium ion binding | IC | molecular_function |
GO:0004674 | protein serine/threonine kinase activity | IEA | molecular_function |
GO:0016772 | transferase activity, transferring phosphorus-cont | IEA | molecular_function |
GO:0007228 | positive regulation of hh target transcription fac | IEA | biological_process |
GO:0042384 | cilium assembly | IEA | biological_process |
GO:0045880 | positive regulation of smoothened signaling pathwa | IEA | biological_process |
GO:0004713 | protein tyrosine kinase activity | IEA | molecular_function |
GO:0005737 | cytoplasm | IDA | cellular_component |
GO:0005515 | protein binding | IEA | molecular_function |
GO:0005488 | binding | IEA | molecular_function |
GO:0007420 | brain development | IEA | biological_process |
GO:0005515 | protein binding | IPI | molecular_function |
GO:0005524 | ATP binding | IEA | molecular_function |
GO:0005634 | nucleus | IDA | cellular_component |
GO:0051090 | regulation of sequence-specific DNA binding transc | IDA | biological_process |
GO:0009791 | post-embryonic development | IEA | biological_process |