Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:STC2_HUMAN
Description:stanniocalcin 2 [Source:HGNC Symbol;Acc:11374]
Location:chr5 q35.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S288GPSGSsEWEDECK2a1(CK2 alphaRegPhos
T28RGTDAtNPPEGStanniocalcinPhosphoSitePlus; SysPTM
S288GPSGSsEWEDEPhosphoSitePlus
T28RGTDAtNPPEGHPRD; phosphoELM; RegPhos; SysPTM
S287QGPSGsSEWEDPhosphoSitePlus
S288GPSGSsEWEDECK2_alphaphosphoELM

Dephosphorylation site
STC2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000265087K265*COSMICSkin Cancer21984974
ENSP00000265087Y297FCOSMICOvarian Cancer21720365

Differential expressed protein
STC2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
STC2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CSK21_HUMANSTC2_HUMANkinase -> substrateRobert H Newman (2013)
ZAGL2_HUMANSTC2_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
STC2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0055074calcium ion homeostasisIEAbiological_process
GO:2001256regulation of store-operated calcium entryIEAbiological_process
GO:0071456cellular response to hypoxiaIEAbiological_process
GO:0005783endoplasmic reticulumIEAcellular_component
GO:0007584response to nutrientTASbiological_process
GO:0033280response to vitamin DIEAbiological_process
GO:0030968endoplasmic reticulum unfolded protein responseIEAbiological_process
GO:0007566embryo implantationIEAbiological_process
GO:0007166cell surface receptor signaling pathwayTASbiological_process
GO:0034976response to endoplasmic reticulum stressIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0005794Golgi apparatusIEAcellular_component
GO:0005179hormone activityIEAmolecular_function
GO:0040015negative regulation of multicellular organism growIEAbiological_process
GO:0006979response to oxidative stressIEAbiological_process
GO:0046697decidualizationIEAbiological_process
GO:0007267cell-cell signalingTASbiological_process
GO:0043434response to peptide hormone stimulusIEAbiological_process
GO:0005576extracellular regionIEAcellular_component
GO:0006874cellular calcium ion homeostasisIEAbiological_process


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