Phosphorylation

Protein information

UniProt/SwissProt ID:	STC2_HUMAN
Description:	stanniocalcin 2 [Source:HGNC Symbol;Acc:11374]
Location:	chr5 q35.1
Node attribute:	substrate

Position	PhosphoPeptide	Catalytic kinase	Source
S288	GPSGSsEWEDE	CK2a1(CK2 alpha	RegPhos
T28	RGTDAtNPPEG	Stanniocalcin	PhosphoSitePlus; SysPTM
S288	GPSGSsEWEDE		PhosphoSitePlus
T28	RGTDAtNPPEG		HPRD; phosphoELM; RegPhos; SysPTM
S287	QGPSGsSEWED		PhosphoSitePlus
S288	GPSGSsEWEDE	CK2_alpha	phosphoELM

STC2_HUMAN do not have dephosphorylation site.

Ensembl ID	Variation	Source	Cancer name	Pubmed
ENSP00000265087	K265*	COSMIC	Skin Cancer	21984974
ENSP00000265087	Y297F	COSMIC	Ovarian Cancer	21720365

STC2_HUMAN is not differential expressed protein.

STC2_HUMAN do not have hyperphosphorylation site.

Source	Target	Relationship	Resource
CSK21_HUMAN	STC2_HUMAN	kinase -> substrate	Robert H Newman (2013)
ZAGL2_HUMAN	STC2_HUMAN	kinase -> substrate	RegPhos

KEGG Pathway

STC2_HUMAN is not in KEGG pathway.

Gene Ontology

GO ID	GO_Term	Evidence	Ontology
GO:0055074	calcium ion homeostasis	IEA	biological_process
GO:2001256	regulation of store-operated calcium entry	IEA	biological_process
GO:0071456	cellular response to hypoxia	IEA	biological_process
GO:0005783	endoplasmic reticulum	IEA	cellular_component
GO:0007584	response to nutrient	TAS	biological_process
GO:0033280	response to vitamin D	IEA	biological_process
GO:0030968	endoplasmic reticulum unfolded protein response	IEA	biological_process
GO:0007566	embryo implantation	IEA	biological_process
GO:0007166	cell surface receptor signaling pathway	TAS	biological_process
GO:0034976	response to endoplasmic reticulum stress	IEA	biological_process
GO:0005515	protein binding	IEA	molecular_function
GO:0005794	Golgi apparatus	IEA	cellular_component
GO:0005179	hormone activity	IEA	molecular_function
GO:0040015	negative regulation of multicellular organism grow	IEA	biological_process
GO:0006979	response to oxidative stress	IEA	biological_process
GO:0046697	decidualization	IEA	biological_process
GO:0007267	cell-cell signaling	TAS	biological_process
GO:0043434	response to peptide hormone stimulus	IEA	biological_process
GO:0005576	extracellular region	IEA	cellular_component
GO:0006874	cellular calcium ion homeostasis	IEA	biological_process

Human Phosphorylation Mediated
Signaling Transduction Network