Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:STAR_HUMAN
Description:steroidogenic acute regulatory protein [Source:HGNC Symbol;Acc:11359]
Location:chr8 p11.23
Node attribute:gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T204LAGMAtDFGNMSTARTPhosphoSitePlus
S57VRRRSsLLGSRPhosphoSitePlus
S61SSLLGsRLEETPhosphoSitePlus
S195AKRRGsTCVLASTARTPhosphoSitePlus

Dephosphorylation site
STAR_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000276449A231PBIOMARTBreast Cancer21930507, 21930502
ENSP00000276449V28ECOSMICOvarian Cancer21720365

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000276449hepatitis C virusNormal vs. Cancercell lineDown17928924
ENSP00000276449Gastric CancerTreatment (none vs. drug-resistant)cell lineUp18309519

Hyperphosphorylation site
STAR_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
HNF4A_HUMANSTAR_HUMANTF -> target geneTRANSFAC
CDX2_HUMANSTAR_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
STAR_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005758mitochondrial intermembrane spaceIEAcellular_component
GO:0015485cholesterol bindingIEAmolecular_function
GO:0061370testosterone biosynthetic processIEAbiological_process
GO:0043434response to peptide hormone stimulusIEAbiological_process
GO:0018963phthalate metabolic processIEAbiological_process
GO:0048545response to steroid hormone stimulusIEAbiological_process
GO:0017085response to insecticideIEAbiological_process
GO:0043025neuronal cell bodyIEAcellular_component
GO:0042542response to hydrogen peroxideIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0030061mitochondrial cristaIEAcellular_component
GO:0007584response to nutrientIEAbiological_process
GO:0044321response to leptin stimulusIEAbiological_process
GO:0071560cellular response to transforming growth factor beIEAbiological_process
GO:0014070response to organic cyclic compoundIEAbiological_process
GO:0006082organic acid metabolic processIEAbiological_process
GO:0007420brain developmentIEAbiological_process
GO:0005739mitochondrionIEAcellular_component
GO:0044344cellular response to fibroblast growth factor stimIEAbiological_process
GO:0044255cellular lipid metabolic processIEAbiological_process
GO:0042493response to drugIEAbiological_process
GO:0045471response to ethanolIEAbiological_process
GO:0006701progesterone biosynthetic processIEAbiological_process
GO:0008203cholesterol metabolic processIEAbiological_process
GO:0060992response to fungicideIEAbiological_process
GO:0034698response to gonadotropin stimulusIEAbiological_process
GO:0071276cellular response to cadmium ionIEAbiological_process
GO:0071371cellular response to gonadotropin stimulusIEAbiological_process
GO:0009635response to herbicideIEAbiological_process
GO:0010628positive regulation of gene expressionIEAbiological_process
GO:0007623circadian rhythmIEAbiological_process
GO:0071373cellular response to luteinizing hormone stimulusIEAbiological_process
GO:0010212response to ionizing radiationIEAbiological_process
GO:0051412response to corticosterone stimulusIEAbiological_process
GO:0006694steroid biosynthetic processTASbiological_process
GO:0048168regulation of neuronal synaptic plasticityIEAbiological_process
GO:0017127cholesterol transporter activityIEAmolecular_function
GO:0006699bile acid biosynthetic processIEAbiological_process
GO:0035457cellular response to interferon-alphaIEAbiological_process
GO:0046677response to antibioticIEAbiological_process
GO:0010033response to organic substanceIEAbiological_process
GO:0016101diterpenoid metabolic processIEAbiological_process
GO:0071372cellular response to follicle-stimulating hormone IEAbiological_process
GO:0008211glucocorticoid metabolic processIEAbiological_process
GO:0005829cytosolIEAcellular_component
GO:0017143insecticide metabolic processIEAbiological_process
GO:0006703estrogen biosynthetic processIEAbiological_process
GO:0050769positive regulation of neurogenesisIEAbiological_process
GO:0042747circadian sleep/wake cycle, REM sleepIEAbiological_process
GO:0006700C21-steroid hormone biosynthetic processTASbiological_process
GO:0009636response to toxinIEAbiological_process
GO:0008584male gonad developmentIEAbiological_process
GO:0071378cellular response to growth hormone stimulusIEAbiological_process
GO:0071407cellular response to organic cyclic compoundIEAbiological_process
GO:0071346cellular response to interferon-gammaIEAbiological_process
GO:0071222cellular response to lipopolysaccharideIEAbiological_process
GO:0010288response to lead ionIEAbiological_process
GO:0032367intracellular cholesterol transportIEAbiological_process
GO:0071549cellular response to dexamethasone stimulusIEAbiological_process
GO:0050810regulation of steroid biosynthetic processIEAbiological_process
GO:0032869cellular response to insulin stimulusIEAbiological_process
GO:0035094response to nicotineIEAbiological_process
GO:0071248cellular response to metal ionIEAbiological_process
GO:0071312cellular response to alkaloidIEAbiological_process
GO:0018879biphenyl metabolic processIEAbiological_process
GO:0018894dibenzo-p-dioxin metabolic processIEAbiological_process
GO:0031667response to nutrient levelsIEAbiological_process
GO:0071236cellular response to antibioticIEAbiological_process
GO:0071333cellular response to glucose stimulusIEAbiological_process
GO:0071872cellular response to epinephrine stimulusIEAbiological_process
GO:0044281small molecule metabolic processTASbiological_process
GO:0008202steroid metabolic processTASbiological_process
GO:0043005neuron projectionIEAcellular_component
GO:0050756fractalkine metabolic processIEAbiological_process
GO:0043627response to estrogen stimulusIEAbiological_process
GO:0071320cellular response to cAMPIEAbiological_process
GO:0018958phenol-containing compound metabolic processIEAbiological_process