Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:STAM2_HUMAN
Description:signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 [Source:HGNC Symbol;Acc:11358]
Location:chr2 q23.3
Node attribute:substrate; PPI(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S161KNGTSsNKNKEPhosphoSitePlus
Y371NEAPVySVYSKPhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM
Y374PVYSVySKLHPPhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM
S375VYSVYsKLHPPPhosphoSitePlus
S372EAPVYsVYSKLPhosphoSitePlus; HPRD; RegPhos
Y290SEPEPvYIDEDHPRD
Y192ETKSLyPSSEIEGFRHPRD; RegPhos; SysPTM
S160AKNGTsSNKNKPhosphoSitePlus
T159AAKNGtSSNKNPhosphoSitePlus
Y191TETKSlYPSSEHPRD
Y291EPEPVyIDEDKPhosphoSitePlus; HPRD; SysPTM
Y192ETKSLyPSSEIPhosphoSitePlus; phosphoELM; RegPhos; SysPTM

Dephosphorylation site
STAM2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000263904D334ACOSMICOvarian Cancer21720365

Differential expressed protein
STAM2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
STAM2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANSTAM2_HUMANkinase -> substrateRegPhos
EGFR_HUMANSTAM2_HUMANkinase -> substrateHPRD; RegPhos
JAK1_HUMANSTAM2_HUMANkinase -> substrateNetPath
STAM2_HUMANJAK1_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04630Jak-STAT signaling pathway
hsa04144Endocytosis

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0042059negative regulation of epidermal growth factor recTASbiological_process
GO:0043231intracellular membrane-bounded organelleIDAcellular_component
GO:0006886intracellular protein transportIEAbiological_process
GO:0031901early endosome membraneIEAcellular_component
GO:0005634nucleusIDAcellular_component
GO:0016197endosomal transportTASbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0005829cytosolTAScellular_component
GO:0016044cellular membrane organizationTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0007173epidermal growth factor receptor signaling pathwayTASbiological_process


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