| UniProt/SwissProt ID: | STABP_HUMAN |
| Description: | STAM binding protein [Source:HGNC Symbol;Acc:16950] |
| Location: | chr2 p13.1 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S247 | LSNSEsIPTID | PhosphoSitePlus; phosphoELM; RegPhos | |
| S2 | MSDHGdV | RegPhos | |
| S2 | HGDV | BMPR1B | HPRD |
| S39 | RRYFRsGVEII | PhosphoSitePlus | |
| S48 | IIRMAsIYSEE | PhosphoSitePlus; phosphoELM; RegPhos | |
| S399 | GFHPHsKDPPL | PhosphoSitePlus | |
| S2 | HGDV | phosphoELM | |
| S245 | GALSNsESIPT | PhosphoSitePlus; phosphoELM; RegPhos | |
| S2 | ____MsDHGDV | PhosphoSitePlus | |
| S245 | GALSNsESIPT | BMPR1B | HPRD; RegPhos |
| S243 | KPGALsNSESI | PhosphoSitePlus; phosphoELM; RegPhos | |
| S48 | IIRMAsIYSEE | BMPR1B | HPRD; RegPhos |
| S247 | LSNSEsIPTID | BMPR1B | HPRD; RegPhos |
| S2 | MSDHGdV | BMPR1B | RegPhos |
| S243 | KPGALsNSESI | BMPR1B | HPRD; RegPhos |
| S19 | RVRALsQLGSA | PhosphoSitePlus | |
| Dephosphorylation site |
| STABP_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000377633 | R255H | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000344742 | R255H | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000386548 | R255H | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000377633 | V27M | COSMIC | Lung Cancer | 20668451 | ENSP00000377636 | R255H | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000377636 | Q156H | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000377633 | R255H | COSMIC | Ovarian Cancer | 21720365 | ENSP00000377633 | Q156H | COSMIC | Pancreatic Cancer |
| Differential expressed protein |
| STABP_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| STABP_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| BMR1B_HUMAN | STABP_HUMAN | kinase -> substrate | RegPhos |
| ZAGL2_HUMAN | STABP_HUMAN | kinase -> substrate | RegPhos |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04144 | Endocytosis |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0008237 | metallopeptidase activity | IEA | molecular_function |
| GO:0016579 | protein deubiquitination | IMP | biological_process |
| GO:0005886 | plasma membrane | IDA | cellular_component |
| GO:0008284 | positive regulation of cell proliferation | TAS | biological_process |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0000281 | cytokinesis after mitosis | IMP | biological_process |
| GO:0006508 | proteolysis | IEA | biological_process |
| GO:0004843 | ubiquitin-specific protease activity | IDA | molecular_function |
| GO:0005769 | early endosome | IEA | cellular_component |
| GO:0032154 | cleavage furrow | IEA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0007259 | JAK-STAT cascade | TAS | biological_process |
| GO:0046872 | metal ion binding | IEA | molecular_function |
| GO:0043066 | negative regulation of apoptotic process | IEA | biological_process |