Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SREC_HUMAN
Description:scavenger receptor class F, member 1 [Source:HGNC Symbol;Acc:16820]
Location:chr17 p13.3
Node attribute:receptor; gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S756GQSPNsAPKAGPhosphoSitePlus
S635REAEEsTGPEEPhosphoSitePlus
S611SGELSsPLRKPPhosphoSitePlus; HPRD; phosphoELM; SysPTM
Y692PVTTIyMLAGKPhosphoSitePlus
S476WGTLTsLGSTLPhosphoSitePlus
S525SGELSsPLRKPHPRD
S520QSRRSsGELSSHPRD
S652FPAAAsPGDSAPhosphoSitePlus
Y818QEEPEyENVVPPhosphoSitePlus
S799VSGCGsPEQDPPhosphoSitePlus
S606QSRRSsGELSSPhosphoSitePlus; HPRD; phosphoELM
S753GSVGQsPNSAPPhosphoSitePlus
T473LQVWGtLTSLGPhosphoSitePlus

Dephosphorylation site
SREC_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000263071C41SCOSMICOvarian Cancer21720365
ENSP00000263071R789KCOSMICSkin Cancer21984974
ENSP00000263071C41SCOSMICOvarian Cancer21720365
ENSP00000263071E307KCOSMICHead and Neck Cancer21798893
ENSP00000263071R789KCOSMICSkin Cancer21984974
ENSP00000263071P577SCOSMICMelanoma21499247

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000323964Lung CancerNormal vs. CancertissueUp12943690

Hyperphosphorylation site
SREC_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CALR_HUMANSREC_HUMANligand -> receptorHPMR
ZN444_HUMANSREC_HUMANTF -> target geneTRANSFAC
SP1_HUMANSREC_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
SREC_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIEAmolecular_function
GO:0006707cholesterol catabolic processICbiological_process
GO:0048680positive regulation of axon regenerationISSbiological_process
GO:0048680positive regulation of axon regenerationIEAbiological_process
GO:0010976positive regulation of neuron projection developmeISSbiological_process
GO:0010976positive regulation of neuron projection developmeIEAbiological_process
GO:0016322neuron remodelingISSbiological_process
GO:0016021integral to membraneIDAcellular_component
GO:0005044scavenger receptor activityIDAmolecular_function
GO:0030169low-density lipoprotein particle bindingIDAmolecular_function
GO:0006898receptor-mediated endocytosisTASbiological_process
GO:0004888transmembrane signaling receptor activityTASmolecular_function
GO:0007155cell adhesionIEAbiological_process
GO:0016358dendrite developmentIEAbiological_process
GO:0016322neuron remodelingIEAbiological_process


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23