| UniProt/SwissProt ID: | SOM2_HUMAN |
| Description: | growth hormone 2 [Source:HGNC Symbol;Acc:4262] |
| Location: | chr17 q23.3 |
| Node attribute: | PPI(source) |
| Phosphorylation site |
| SOM2_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| SOM2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000410618 | *203L | COSMIC | Hepatocellular Carcinoma | 21822264 | ENSP00000333157 | N125K | COSMIC | Head and Neck Cancer | 21798897 | ENSP00000394122 | T177K | COSMIC | Ovarian Cancer | 21720365 | ENSP00000333157 | G209R | COSMIC | Head and Neck Cancer | 21798897 | ENSP00000394122 | K154R | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000333157 | W112L | COSMIC | Pancreatic Cancer | ENSP00000333157 | R240G | BIOMART | Breast Cancer | 21930507, 21930502 |
| Differential expressed protein |
| SOM2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| SOM2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| SOM2_HUMAN | GHR_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04060 | Cytokine-cytokine receptor interaction |
| hsa04630 | Jak-STAT signaling pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005179 | hormone activity | IEA | molecular_function |
| GO:0060397 | JAK-STAT cascade involved in growth hormone signal | TAS | biological_process |
| GO:0005576 | extracellular region | TAS | cellular_component |