| UniProt/SwissProt ID: | SNX13_HUMAN |
| Description: | sorting nexin 13 [Source:HGNC Symbol;Acc:21335] |
| Location: | chr7 p21.1 |
| Node attribute: | effector |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S353 | IQRLQsGKEIN | PhosphoSitePlus | |
| T359 | GKEINtVKLAA | PhosphoSitePlus; HPRD; phosphoELM | |
| Y681 | LAHYVyDFLEN | PX | PhosphoSitePlus |
| Y679 | PALAHyVYDFL | PX | PhosphoSitePlus |
| Dephosphorylation site |
| SNX13_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000398789 | F837L | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000398789 | H429Y | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000398789 | P155S | COSMIC | Central Nervous System Neoplasms | 18772890 | ENSP00000398789 | L652* | COSMIC | Renal Cancer | ENSP00000398789 | A831V | COSMIC | Central Nervous System Neoplasms | 18772396 |
| Differential expressed protein |
| SNX13_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| SNX13_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| GNAS2_HUMAN | SNX13_HUMAN | Gprotein -> effector | gpDB |
| GNAS1_HUMAN | SNX13_HUMAN | Gprotein -> effector | gpDB |
| Function Annotation |
| KEGG Pathway |
| SNX13_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0031901 | early endosome membrane | IEA | cellular_component |
| GO:0043547 | positive regulation of GTPase activity | IDA | biological_process |
| GO:0007154 | cell communication | IEA | biological_process |
| GO:0038032 | termination of G-protein coupled receptor signalin | IEA | biological_process |
| GO:0005769 | early endosome | IDA | cellular_component |
| GO:0035091 | phosphatidylinositol binding | IDA | molecular_function |
| GO:0005743 | mitochondrial inner membrane | IEA | cellular_component |
| GO:0004129 | cytochrome-c oxidase activity | IEA | molecular_function |
| GO:0006886 | intracellular protein transport | IMP | biological_process |