| UniProt/SwissProt ID: | SNTA1_HUMAN |
| Description: | syntrophin, alpha 1 [Source:HGNC Symbol;Acc:11167] |
| Location: | chr20 q11.21 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T89 | QRRRVtVRKAD | PDZ | PhosphoSitePlus |
| S411 | GVQEVsTACTW | PhosphoSitePlus | |
| S200 | LQRQPsSPGPT | PhosphoSitePlus | |
| S193 | DSPPAsPLQRQ | p38g(MAPK12 | RegPhos |
| S201 | QRQPSsPGPTP | PhosphoSitePlus | |
| S193 | DSPPAsPLQRQ | p38g | RegPhos |
| S201 | QRQPSsPGPTP | MAPK_group | phosphoELM; RegPhos |
| S201 | QRQPSsPGPTP | MAPK12 | HPRD; phosphoELM |
| S101 | GGLGIsIKGGR | PDZ | PhosphoSitePlus |
| T205 | SSPGPtPRNFS | PhosphoSitePlus | |
| T415 | VSTACtWNGRP | PhosphoSitePlus | |
| S189 | SVGWDsPPASP | PhosphoSitePlus; HPRD; phosphoELM; RegPhos | |
| S201 | QRQPSsPGPTP | p38g(MAPK12 | RegPhos |
| S291 | TSTAGsQDIKQ | PhosphoSitePlus | |
| T346 | APLIAtRLVHS | HPRD | |
| T183 | NSTGGtSVGWD | PhosphoSitePlus | |
| T346 | APLIAtRLVHS | PH | PhosphoSitePlus |
| S101 | GGLGIsIKGGR | HPRD | |
| S193 | DSPPAsPLQRQ | MAPK_group | phosphoELM; RegPhos |
| S184 | STGGTsVGWDS | PhosphoSitePlus | |
| S21 | RAGAGsGAGGE | PhosphoSitePlus | |
| S201 | QRQPSsPGPTP | p38g | RegPhos |
| T412 | VQEVStACTWN | PhosphoSitePlus | |
| S193 | DSPPAsPLQRQ | MAPK12 | HPRD; phosphoELM |
| T312 | GGTAPtLALLT | PhosphoSitePlus | |
| S193 | DSPPAsPLQRQ | PhosphoSitePlus; phosphoELM; RegPhos | |
| Y175 | KDVSPyFKNST | PhosphoSitePlus | |
| Dephosphorylation site |
| SNTA1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000217381 | S357A | COSMIC | Hepatocellular Carcinoma | 21822264 | ENSP00000217381 | G186D | COSMIC | Melanoma | 21499247 |
| Differential expressed protein |
| SNTA1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| SNTA1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ZAGL2_HUMAN | SNTA1_HUMAN | kinase -> substrate | RegPhos |
| MK12_HUMAN | SNTA1_HUMAN | kinase -> substrate | HPRD; Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| SNTA1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0005856 | cytoskeleton | IEA | cellular_component |
| GO:0045211 | postsynaptic membrane | IEA | cellular_component |
| GO:0005622 | intracellular | IDA | cellular_component |
| GO:0003779 | actin binding | IEA | molecular_function |
| GO:0042383 | sarcolemma | IEA | cellular_component |
| GO:0003117 | regulation of vasoconstriction by circulating nore | IEA | biological_process |
| GO:0006936 | muscle contraction | TAS | biological_process |
| GO:0007528 | neuromuscular junction development | IEA | biological_process |
| GO:0005516 | calmodulin binding | IEA | molecular_function |
| GO:0005543 | phospholipid binding | IEA | molecular_function |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0030054 | cell junction | IEA | cellular_component |