Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SNTA1_HUMAN
Description:syntrophin, alpha 1 [Source:HGNC Symbol;Acc:11167]
Location:chr20 q11.21
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T89QRRRVtVRKADPDZPhosphoSitePlus
S411GVQEVsTACTWPhosphoSitePlus
S200LQRQPsSPGPTPhosphoSitePlus
S193DSPPAsPLQRQp38g(MAPK12RegPhos
S201QRQPSsPGPTPPhosphoSitePlus
S193DSPPAsPLQRQp38gRegPhos
S201QRQPSsPGPTPMAPK_groupphosphoELM; RegPhos
S201QRQPSsPGPTPMAPK12HPRD; phosphoELM
S101GGLGIsIKGGRPDZPhosphoSitePlus
T205SSPGPtPRNFSPhosphoSitePlus
T415VSTACtWNGRPPhosphoSitePlus
S189SVGWDsPPASPPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S201QRQPSsPGPTPp38g(MAPK12RegPhos
S291TSTAGsQDIKQPhosphoSitePlus
T346APLIAtRLVHSHPRD
T183NSTGGtSVGWDPhosphoSitePlus
T346APLIAtRLVHSPHPhosphoSitePlus
S101GGLGIsIKGGRHPRD
S193DSPPAsPLQRQMAPK_groupphosphoELM; RegPhos
S184STGGTsVGWDSPhosphoSitePlus
S21RAGAGsGAGGEPhosphoSitePlus
S201QRQPSsPGPTPp38gRegPhos
T412VQEVStACTWNPhosphoSitePlus
S193DSPPAsPLQRQMAPK12HPRD; phosphoELM
T312GGTAPtLALLTPhosphoSitePlus
S193DSPPAsPLQRQPhosphoSitePlus; phosphoELM; RegPhos
Y175KDVSPyFKNSTPhosphoSitePlus

Dephosphorylation site
SNTA1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000217381S357ACOSMICHepatocellular Carcinoma21822264
ENSP00000217381G186DCOSMICMelanoma21499247

Differential expressed protein
SNTA1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SNTA1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANSNTA1_HUMANkinase -> substrateRegPhos
MK12_HUMANSNTA1_HUMANkinase -> substrateHPRD; Robert H Newman (2013)

Function Annotation
KEGG Pathway
SNTA1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005737cytoplasmIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0005856cytoskeletonIEAcellular_component
GO:0045211postsynaptic membraneIEAcellular_component
GO:0005622intracellularIDAcellular_component
GO:0003779actin bindingIEAmolecular_function
GO:0042383sarcolemmaIEAcellular_component
GO:0003117regulation of vasoconstriction by circulating noreIEAbiological_process
GO:0006936muscle contractionTASbiological_process
GO:0007528neuromuscular junction developmentIEAbiological_process
GO:0005516calmodulin bindingIEAmolecular_function
GO:0005543phospholipid bindingIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0030054cell junctionIEAcellular_component


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